Protein Info for ABZR86_RS07320 in Dyella japonica UNC79MFTsu3.2

Annotation: endopeptidase La

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 835 PF02190: LON_substr_bdg" amino acids 18 to 208 (191 residues), 185.5 bits, see alignment E=2.9e-58 TIGR00763: endopeptidase La" amino acids 19 to 799 (781 residues), 1019.7 bits, see alignment E=0 PF00004: AAA" amino acids 360 to 496 (137 residues), 75.7 bits, see alignment E=1.2e-24 PF07728: AAA_5" amino acids 360 to 484 (125 residues), 36.1 bits, see alignment E=1.5e-12 PF05362: Lon_C" amino acids 597 to 800 (204 residues), 330 bits, see alignment E=1.3e-102 PF13541: ChlI" amino acids 655 to 768 (114 residues), 28 bits, see alignment E=4.3e-10

Best Hits

Swiss-Prot: 74% identical to LON_XANOR: Lon protease (lon) from Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)

KEGG orthology group: K01338, ATP-dependent Lon protease [EC: 3.4.21.53] (inferred from 75% identity to xal:XALc_0589)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type I" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FZ68 at UniProt or InterPro

Protein Sequence (835 amino acids)

>ABZR86_RS07320 endopeptidase La (Dyella japonica UNC79MFTsu3.2)
MAKNAPLPVATGAALDALPVLPLRDVVVYPHMVIPLFVGRDKSMRALERAMEGERQILLV
AQKSPDIDDPAVADLHQIGTLAGVLQLLKLPDGTVKVLVEGQARVSVEKYEEDGGMLMAT
SRIIEPQYSAKERELDVVSRTLVSLFEQLVKQSRKLPPEVLATLSGIDDPSRLADSIAAH
LSVRMADKQKVLETADVGQRLELLIGLVDGEMDLQQVEKRIRGRVKSQMEKSQREYYLNE
QMKAIQKELGESEEGPNEVEELQKKIDNAGMPKPVLAKARQEFSKLRQMSPMSAEATVVR
NYLDWLVGVPWKKRSKVRKDLQLAQDVLDADHFGLEKVKERILEYLAVQQRVNTMKGPIL
CLVGPPGVGKTSLGQSIAKATNRKFVRMSLGGVRDEAEIRGHRRTYIGSMPGRIVQNLNK
VGTKNPLFVLDEIDKMSMDFRGDPSSALLEVLDPEQNHTFNDHYLEVDLDLSEVMWIATA
NSLNIPGPLLDRMEVIRIPGYTEDEKLGIAQKYLLPKQLKANGLKEGELSVDGEAIRDIV
RYYTRESGVRNLEREVSKICRKVVKELTLGEAKKAAKSKAKVETAKAGKVKKLSGIKVTS
DNLEHYLGVRRFDFGRKELQNEVGLVTGLAWTQVGGDLLSIEASIVPGKGRLVHTGQLGD
VMKESIQAALSVVRARADRFGIDPEFHQNLDIHIHVPEGATPKDGPSAGIAMCTALVSAL
TKVPVRSEVAMTGEITLRGRVLPIGGLKEKLLAAHRGGITTVIIPEENKKDLADIPANIT
GQLEIHAVRWIDEVLDIALERPLQPRQASEEAAATKVETKVDGNEDSAETPARPH