Protein Info for ABZR86_RS06445 in Dyella japonica UNC79MFTsu3.2

Annotation: heme lyase CcmF/NrfE family subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 656 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 21 to 26 (6 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 74 to 90 (17 residues), see Phobius details amino acids 96 to 113 (18 residues), see Phobius details amino acids 121 to 143 (23 residues), see Phobius details amino acids 176 to 197 (22 residues), see Phobius details amino acids 209 to 229 (21 residues), see Phobius details amino acids 248 to 264 (17 residues), see Phobius details amino acids 273 to 292 (20 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 351 to 374 (24 residues), see Phobius details amino acids 389 to 413 (25 residues), see Phobius details amino acids 425 to 444 (20 residues), see Phobius details amino acids 450 to 469 (20 residues), see Phobius details amino acids 489 to 508 (20 residues), see Phobius details amino acids 613 to 633 (21 residues), see Phobius details TIGR00353: cytochrome c-type biogenesis protein CcmF" amino acids 53 to 638 (586 residues), 719.6 bits, see alignment E=1.8e-220 PF01578: Cytochrom_C_asm" amino acids 89 to 295 (207 residues), 175.8 bits, see alignment E=9.6e-56 PF16327: CcmF_C" amino acids 315 to 635 (321 residues), 387.3 bits, see alignment E=6.1e-120

Best Hits

KEGG orthology group: K02198, cytochrome c-type biogenesis protein CcmF (inferred from 75% identity to xca:xccb100_2600)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmF" in subsystem Biogenesis of c-type cytochromes or Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1Y5L3 at UniProt or InterPro

Protein Sequence (656 amino acids)

>ABZR86_RS06445 heme lyase CcmF/NrfE family subunit (Dyella japonica UNC79MFTsu3.2)
MTPELGQLALILALLLALAQGVLPLLGAWRGNGALMAVARPAAAGQAVFVALAFGVLSWA
FLHFDFSVRYVADNSNLALPWYYRLAAVWGAHEGSLLLWIFILNLWTVALAALSHKLPDV
FVARVLGVLGLIAVGFIAFILFTSNPFERLLPMPPDGGDLNPVLQDPGMTFHPPVLYMGY
VGFSVAFAFSIAALLGGELEQAWVRWARPWTNVAWGFLSAGIVAGSWWAYAELGWGGWWF
WDPVENASFMPWLVGAALIHAQAVTEKRGALRAWTILLSIFAFSLSLLGTFLVRSGVLTS
VHAFASDPKRGLFILCFLAVVVGGSLLLYALRAPKVAGGKPFGVVSRETAILIGNLMLTV
AAAMVLLGTLFPLLGDALNLGKISVGPPYFGFLFTLLMIPIVLLLPFGPYLRWGEKGGLP
PLKNVAVRAGIAALACAIAAAFTTGWALKAIAGTAAAVWCCVGTLLYVLKRWREMPAGRR
YPAEMAGMLLAHFGVGVFLAGVLLTEALSVERDVRMAPGQVQTIGGYDFRFDGVHVADGP
NWQGDQGTVTVMRDDREIAVMHPQKRTYTRGQVQTESAIDAGVTRDLYVALGEPMDRNDP
EGAWALRLYHKPFVRWIWAGGLLMMLGGFFSAADKRFRLRREATEKLPASAQESHA