Protein Info for ABZR86_RS06245 in Dyella japonica UNC79MFTsu3.2

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 3 to 356 (354 residues), 421.7 bits, see alignment E=1.3e-130 PF13177: DNA_pol3_delta2" amino acids 20 to 178 (159 residues), 147.8 bits, see alignment E=7.5e-47 PF00004: AAA" amino acids 42 to 172 (131 residues), 41.6 bits, see alignment E=4.3e-14 PF12169: DNA_pol3_gamma3" amino acids 234 to 358 (125 residues), 90.1 bits, see alignment E=3e-29 PF12170: DNA_pol3_tau_5" amino acids 439 to 554 (116 residues), 47.1 bits, see alignment E=6.8e-16

Best Hits

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1Y1H6 at UniProt or InterPro

Protein Sequence (563 amino acids)

>ABZR86_RS06245 DNA polymerase III subunit gamma/tau (Dyella japonica UNC79MFTsu3.2)
MSYQVLARKWRPRKFAELVGQEHVVRALTNALDTGRMHHAYLFTGTRGVGKTTIARIFAK
SLNCERGESADPCGECAVCTAVDAGRFVDLLEIDAASNTGVDDVREVIENAQYAPARGRF
KVYLVDEVHMLSKPAFNALLKTLEEPPPHVKFLLATTDPQKLPVTVLSRCLKFNLKRLLP
EQISGQMRHILGAESIAYEDGAIVELARAADGSLRDGLSLLDQAIAYGGGALKVDDVRAM
LGSVARGQVLGVLDALAAGDGDQLMAECARIASFSPDFGGVLDDLAAVLHRLQLFQLVPG
YRPEGDGGDEAALAALAERLGPEDVQLYYQIAIGGRRDLALAPDARTGFEMALLRMLAFR
PAGEGEPTRAERPAAAPRPAAAPAPAPARSAPPMPASAPAPAMERPAPRQAETLPPRMEP
APVPAPRAAPALDSRGLPHWDSLIEQASLRGPMGQLAQNAVLREREGSTLVLALQPMYMH
LAVEPMVGQMEERISQALGERIRLRFVDDRSGGGETPAARAANARSVAQSAAEQSIEEDP
LVQSLRREFGARVLPQSVKPFEP