Protein Info for ABZR86_RS06135 in Dyella japonica UNC79MFTsu3.2

Annotation: DNA polymerase III subunit delta'

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF13177: DNA_pol3_delta2" amino acids 7 to 171 (165 residues), 148.6 bits, see alignment E=8.6e-48 TIGR00678: DNA polymerase III, delta' subunit" amino acids 11 to 201 (191 residues), 200.7 bits, see alignment E=8.4e-64

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 47% identity to smt:Smal_0878)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1XZ23 at UniProt or InterPro

Protein Sequence (311 amino acids)

>ABZR86_RS06135 DNA polymerase III subunit delta' (Dyella japonica UNC79MFTsu3.2)
MSAMPWHAELWERLQARRRRDAMPHALLLCGPAGLGKRDFMRRFARGLLCQQAVDGEACG
RCRSCLLLDAGTHPDLVTLSFGLRKDGVQRSDIVVDQIRELSSRLAMASQFGGWQIATID
PADAMNTAAANALLKTLEEPSQNTLLLLVADAPWRMPQTIRSRCQRIEFQVPAREEALAW
LQGEGVKDPVAALDAAGGNPGLARAWAEEGALARRQEVRKDLAALAAGRGETMEVVRRWL
DNEPAQRLWFAAQAAADEARGRAGANNGPLASHLDAEALDDWYRAANHARDALRGPLRGD
LLLLELLSRWR