Protein Info for ABZR86_RS06060 in Dyella japonica UNC79MFTsu3.2

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 120 to 137 (18 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 222 to 240 (19 residues), see Phobius details amino acids 261 to 279 (19 residues), see Phobius details amino acids 291 to 312 (22 residues), see Phobius details amino acids 319 to 342 (24 residues), see Phobius details amino acids 349 to 368 (20 residues), see Phobius details amino acids 388 to 407 (20 residues), see Phobius details amino acids 425 to 444 (20 residues), see Phobius details amino acids 512 to 533 (22 residues), see Phobius details amino acids 574 to 594 (21 residues), see Phobius details amino acids 674 to 695 (22 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 7 to 689 (683 residues), 783.4 bits, see alignment E=1.2e-239 PF00662: Proton_antipo_N" amino acids 71 to 121 (51 residues), 80.4 bits, see alignment 7.2e-27 PF00361: Proton_antipo_M" amino acids 137 to 423 (287 residues), 283.5 bits, see alignment E=1.9e-88

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 64% identity to tgr:Tgr7_0997)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1XXT2 at UniProt or InterPro

Protein Sequence (697 amino acids)

>ABZR86_RS06060 NADH-quinone oxidoreductase subunit L (Dyella japonica UNC79MFTsu3.2)
MAISTSILLVIALAPLLGCLLAGFLGKFIGRAGAHSATILGVAISCALSMYVLYQLCTGA
VPVYNQNIYTWFEIGKYTATVGFLIDKLSAMMMVVVTFVSLLVHIYTIGYMAEDDGYQRF
FSYISLFTFSMLMLVMSNNFMQLFFGWEAVGLVSYLLIGFWFKRPTAIFANLKAFLVNRV
GDFGFLLGIAAILYFLGTLDYSTAFANAPSLVGKTLQITQNHAWDAATVIGVLLFIGAMG
KSAQVPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVARMSPIFELSEGALSFIMVIGA
TGALFTGLIGIVQNDIKRVVAYSTLSQLGYMTVALGVSAYAGAVFHLMTHAFFKALLFLG
AGSVIIAMHHEQDMRYMGGLRKYMPVTWITMWIGSLALCGVPFFAGFYSKDAIIEAVGES
HRWGAGYAYACVLIGAFVTALYTFRQMYLTFHGKERFTVVADHGHGHGEHAAHHDAHHGD
AHHGEHHDDAHHDDHGHHEPGVLHHAPKESPWVVTLPLVLLAIPSIVIGAIGAKSMLYSG
WFGEAIHVNEANNVLAELSHEFHDWFSAALHGFAQWPFVLVALAFAIQTYIYLFNPAVAD
KIKSALKPLWTVLDRKYWIDDVYFAVFAKGGVKLGRALWKGGDAAVIDGVLVDGSASLVQ
RVARGVRALQSGYLYHYAFAMILGLILLLGGYWLVGQ