Protein Info for ABZR86_RS06050 in Dyella japonica UNC79MFTsu3.2

Annotation: NADH-quinone oxidoreductase subunit NuoN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01770: proton-translocating NADH-quinone oxidoreductase, chain N
  • amino acids 8 to 473 (466 residues), 482.1 bits, E=1.1e-148
• PF00361: Proton_antipo_M
  • amino acids 132 to 425 (294 residues), 260.3 bits, E=1.1e-81

Best Hits

Swiss-Prot: 54% identical to NUON2_NITOC: NADH-quinone oxidoreductase subunit N 2 (nuoN2) from Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)

KEGG orthology group: K00343, NADH dehydrogenase I subunit N [EC: 1.6.5.3] (inferred from 60% identity to xca:xccb100_1646)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• NADH to cytochrome bd oxidase electron transfer I (2/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

See A0A1I1XX94 at UniProt or InterPro

Protein Sequence (487 amino acids)

>ABZR86_RS06050 NADH-quinone oxidoreductase subunit NuoN (Dyella japonica UNC79MFTsu3.2)
MPNLNDILIMLPELYLVAAACLLLLVDAFMKAEQPVLLGLNGREVLHWTSILVVLVAIYL
VISGQPEQPVRAFGGMFVRDGVAEILKVFALLCVALIFIYARSYLADRKLFVGEFYTLMI
FAVIGVMLLVSAGNLITVYLGLELLTLSSYALVALNRDSKLSSEAAVKYFVLGALASGML
LYGMSMVYGATATLDLATLHNAAAHTGVPNLLLFGLIFMIIGIGFKLGAAPFHMWIPDVY
QGSPTAVTIFIGSAPKLAAFGMAYRLLESGLGDLSAHWQQMLAALAVLSLAIGNLVAIVQ
TNLKRLLAYSTISHMGYLLLGLVNAGPEGYASALFYAISYALMGTAAFGVILALARAGFE
CEEIDDLKGLNQRSPWMAFLMMLVMFSLAGVPPLFGFFAKFLVLQSAIHAGMLWLAIVGA
VFAIIGLYYYLRVVKVMYFDAPVEGTELKPQRDPAMRLVLSLNALTLLVLGLYWGPLLGW
CKSVFPG