Protein Info for ABZR86_RS05905 in Dyella japonica UNC79MFTsu3.2

Annotation: assimilatory sulfite reductase (NADPH) flavoprotein subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 596 TIGR01931: sulfite reductase [NADPH] flavoprotein, alpha-component" amino acids 11 to 596 (586 residues), 743.9 bits, see alignment E=7.4e-228 PF00258: Flavodoxin_1" amino acids 65 to 189 (125 residues), 120 bits, see alignment E=1.5e-38 PF00667: FAD_binding_1" amino acids 230 to 299 (70 residues), 60.6 bits, see alignment E=2.6e-20 PF00175: NAD_binding_1" amino acids 454 to 560 (107 residues), 60.8 bits, see alignment E=2.8e-20

Best Hits

Swiss-Prot: 43% identical to CYSJ_ALIF1: Sulfite reductase [NADPH] flavoprotein alpha-component (cysJ) from Aliivibrio fischeri (strain ATCC 700601 / ES114)

KEGG orthology group: K00380, sulfite reductase (NADPH) flavoprotein alpha-component [EC: 1.8.1.2] (inferred from 58% identity to mxa:MXAN_2335)

Predicted SEED Role

"Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1XUW8 at UniProt or InterPro

Protein Sequence (596 amino acids)

>ABZR86_RS05905 assimilatory sulfite reductase (NADPH) flavoprotein subunit (Dyella japonica UNC79MFTsu3.2)
MNAVVSQESLASPLAADKAAQLHRLLEGLAPHELYWVAARSAALAARGPQPAQVQAAATT
ERVTVLYGSQTGNARRVAEQLAKKLEASGLPARLVRADAYPQRELTQERQLFVVISTQGE
GEPPDDARGLVDFIAGRRAPRLPALRYAVLGLGDSSYPQFCLIGRQLDARLAELGATRLD
PLAEADVDLDEVAAPWTAKALERAHEVLKAPAAAVRAPLLQAVPSHAAHDRENPFAAAVL
ANQRIVSRDSAREVLHLELSLESSGLSYRPGDALGVWPRNPPALVQQWLELLRLDGEAEV
THSGRTLPLVRWLAEERELTRLARGFALAHARTGGDAALVRLLDDPATLSTLLDTHQPID
LLRRHPGRWDAAALVAALRPLTPRLYSIASSAAAVGDEVHLTVATVDYQAFGERHWGAAS
AFLAASAEDARVPVFVEANERFHLPADDARDVIMIGPGTGVAPFRGFVQERRESGARGRN
WLFFGNRHFSDDFLYQVEWQEALKQGALHRLDLAFSRDGADKVYVQHRLRERGKELYAWL
SEGAHLYVCGDATHMARDVHAALVDIAAEHGGLSREDAGAWLADLLQQGRYARDVY