Protein Info for ABZR86_RS05650 in Dyella japonica UNC79MFTsu3.2

Annotation: molecular chaperone DnaK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 640 TIGR02350: chaperone protein DnaK" amino acids 3 to 602 (600 residues), 953.7 bits, see alignment E=1.7e-291 PF00012: HSP70" amino acids 4 to 600 (597 residues), 884.4 bits, see alignment E=3.3e-270 PF06723: MreB_Mbl" amino acids 121 to 377 (257 residues), 40.2 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 83% identical to DNAK_XANOM: Chaperone protein DnaK (dnaK) from Xanthomonas oryzae pv. oryzae (strain MAFF 311018)

KEGG orthology group: K04043, molecular chaperone DnaK (inferred from 83% identity to xop:PXO_01185)

MetaCyc: 74% identical to chaperone protein DnaK (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1XQA0 at UniProt or InterPro

Protein Sequence (640 amino acids)

>ABZR86_RS05650 molecular chaperone DnaK (Dyella japonica UNC79MFTsu3.2)
MGKIIGIDLGTTNSCVAIMDGSTAKVIENSEGDRTTPSIVAFTKDGEVLVGAPAKRQSVT
NPKNTFYAVKRLIGRKFTDAEVQKDLHIVPYGIVAHDNGDAWVATADGKKMAPQEISAKV
LMKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAY
GLDKKGGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLATNGDTFLGGEDFDLRVIDY
LVEEFKKDQGMDLRKDPLALQRLKDAAERAKIELSSSHQTEVNLPYVTADASGPKHLNIK
LTRAKLEALVEDLVKRTIEPCRTALNDAGLRVSDIDEVILVGGQTRMPKVQESVKDFFGK
EPRKDVNPDEAVAVGAAIQGGVLGGSVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTVP
TKASQVFSTADDNQTAVTVHVLQGERERASANKSLGKFDLQGIDAAPRGMPQIEVTFDID
ANGILHVSAKDKKTGKEQKIEIKAGSGLSEEEIARMVADAEANKEEDRKFQELVSTRNKA
DQLVHATRSALKEHGGKVPGEQLSTIEGALAELEKAKDGDDKAAIESKIEKLEQAAQSLN
AVAQGAGAGGPQAGPQGGASGPADDVVDAEFTEVKGDDKK