Protein Info for ABZR86_RS04520 in Dyella japonica UNC79MFTsu3.2

Annotation: formate dehydrogenase accessory protein FdhE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF04216: FdhE" amino acids 22 to 307 (286 residues), 325.8 bits, see alignment E=1.9e-101 TIGR01562: formate dehydrogenase accessory protein FdhE" amino acids 24 to 307 (284 residues), 245.1 bits, see alignment E=6.4e-77

Best Hits

KEGG orthology group: K02380, FdhE protein (inferred from 60% identity to msl:Msil_3328)

Predicted SEED Role

"formate dehydrogenase formation protein FdhE" in subsystem Formate hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1X5D4 at UniProt or InterPro

Protein Sequence (308 amino acids)

>ABZR86_RS04520 formate dehydrogenase accessory protein FdhE (Dyella japonica UNC79MFTsu3.2)
MRQAEAPPSGKWTGPAHAGVKAPEPIVLPDPARRFAATAQRLEQLAEGHPMAAWLRFLGR
LARAQHEAATTLAPGAALDPAAIAQAIDARIPPLAADGHRRDASWREGLARLLERIDRDA
LPDAALQVIEQLQRSDAAAQDRLADRFLRGGLAADDAGAAIYVAAALQVYFTCAAARLQA
EDLRLLEERGLCPCCGSPPVAGVVTAGGTTPGMRYLHCSLCSTAWNHVRAVCITCGGTRH
LALQAIDGDAGLVKAETCGECHTYAKLLYQIHDMQADPHADDLASFGLDILVAEAGFARH
AQNPLLLL