Protein Info for ABZR86_RS03585 in Dyella japonica UNC79MFTsu3.2

Annotation: FdhF/YdeP family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01701: oxidoreductase alpha (molybdopterin) subunit
  • amino acids 21 to 765 (745 residues), 992.9 bits, E=4.5e-303
• PF00384: Molybdopterin
  • amino acids 117 to 498 (382 residues), 83.7 bits, E=1.4e-27
• PF01568: Molydop_binding
  • amino acids 650 to 759 (110 residues), 45.9 bits, E=5.2e-16

Best Hits

Swiss-Prot: 61% identical to YDEP_ECO57: Protein YdeP (ydeP) from Escherichia coli O157:H7

KEGG orthology group: K00123, formate dehydrogenase, alpha subunit [EC: 1.2.1.2] (inferred from 68% identity to bgf:BC1003_3837)

Predicted SEED Role

"Putative formate dehydrogenase oxidoreductase protein" in subsystem Formate hydrogenase

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (4/15 steps found)
• purine nucleobases degradation II (anaerobic) (9/24 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See A0A1I1Z9S8 at UniProt or InterPro

Protein Sequence (774 amino acids)

>ABZR86_RS03585 FdhF/YdeP family oxidoreductase (Dyella japonica UNC79MFTsu3.2)
MSSQPKDLDLEKSIQPYDGPAGGWGALRAVAKAIREQMAVARSVEALQRVNKPLGFDCPG
CAWPDPRHTSSFEFCENGAKAVTWEATSKRTTPEFFAQHTLSELWEWTDHALEDQGRLTH
PMAYDAVQDKYLPVSWDEAATRIGAALRALPEPTMAEFYASGRASNEAAFLYQLFAREYG
CNNFPDCSNMCHEASSVGLPEAIGVGKGTVQLEDFEQADAVFCIGHNPGTNHPRMLGTLR
EVSLRGVPIVVLNPMPERGLERFTSPQDPAEMLTGRSVPIATTYFKPKIGGDIATMKGMM
KWLFEADAADLAGGGAGLLDRAFIAEHTTGLEALRDDVQATSWESIERASGLTRAEIEVA
AGIYAAAEKVIFCYGMGITQHRHGVENVQQLVNLLLLRGNIGKPGAGICPLRGHSNVQGD
RTVGITEKPNAALLDGIRRVYGFEPPSAHGHDAVAAVKAIGEGRSKALLCLGGNLAVAMS
DPQATFPAMRQLDLVVHVATKLNRSHLLPARAAFLLPCLGRTEIDLQAAGPQSVTVEDSM
SMVHASQGRLRPASEHLRSEPAIVALLARATLPQSKVDWEGLAGDYDRIRDDIEAVFPIF
ANYNERVRQPGGFHLENAAALRRWNTPDGKARFLLARGLDEATPATADLLMLATVRSHDQ
YNTTIYGYNDRYRGITGRRDVVFVNPDDLAGRGLREGDRIDVEASRVDGTPNGRAVRGLV
AVPYGIARGSVAMYFPEGNGLLALDEHDARSGTPGYKSIPVRLSASSAPVAPEA