Protein Info for ABZR86_RS03525 in Dyella japonica UNC79MFTsu3.2

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 756 transmembrane" amino acids 24 to 39 (16 residues), see Phobius details PF20256: MoCoBD_2" amino acids 52 to 197 (146 residues), 50.7 bits, see alignment E=2e-17 amino acids 600 to 680 (81 residues), 57.8 bits, see alignment E=1.3e-19 PF02738: MoCoBD_1" amino acids 341 to 558 (218 residues), 111.2 bits, see alignment E=4.4e-36

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 62% identity to vap:Vapar_3841)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1ZF82 at UniProt or InterPro

Protein Sequence (756 amino acids)

>ABZR86_RS03525 xanthine dehydrogenase family protein molybdopterin-binding subunit (Dyella japonica UNC79MFTsu3.2)
MNVRFDQPLGESQPDNPSRREALKLGGLVVAFLWLGGGAKVLGRAAAQGPVAAGDAAFAP
NAFIRVGTDGAVHLVMPSIEMGQGAYSGQATLLAEEMDLGLDQVVVEHAPANRKLYANPL
LGEQATGGSTTIRFCWTTLRQAGAAARALLVGAAAAKWKVDPAQCTVARGVIRHEASGRS
LGYGEVANAAAQLPVPDKVQEKDAAQFALIGKPLRRVDTAGKVDGSLQFGIDLRVPDMKV
ATVKACPTFGGKLVAVDDSRARQVPGFVAVLKIDNAVAAVGEHFWAAKQALDALDITWDH
GPNAQYSTEQLFKDLAEASKHGTPIPGKAVGNVDGVKGKALEATYQLPLLAHATMEPQNA
IVHVRPDGCDIWTGTQVPARCVDVAAKLTGLKPESIVVHNQYMGGGFGRRLFEDPVEQAV
AFARQVSYPLKMVWTREEDIAHDRYRPAYYDRIAATLGDDGKPVAWTHRIASGSVLATFA
PGAMGKNGMDSDAIECAADVPYEFPNMKVEWVRHDMPEGVHLGWWRGVGPVHNVFVVESF
MDELAHAAGKDPLVYRREQLQKNPRALGVLNLAAEKAGWGKGSLPARVGRGVAVAAPFGS
YLCVIVEAEVSPQGEVKLRRAVAAVDCGIAVNPNTVAAQVQGGLIFGWTAALYNGITIKH
GAVEQHNFNDYRMMRINETPALEVHLVDSKEAPGGIGETGTVMAFPALFNALFAATGVRL
RSYPIDRAALVQGPDALKAVITQATDRAAAAKEGMA