Protein Info for ABZR86_RS01755 in Dyella japonica UNC79MFTsu3.2

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 PF00027: cNMP_binding" amino acids 52 to 135 (84 residues), 49.7 bits, see alignment E=4.5e-17 PF13545: HTH_Crp_2" amino acids 165 to 238 (74 residues), 63 bits, see alignment E=3e-21 PF00325: Crp" amino acids 190 to 221 (32 residues), 35.8 bits, see alignment 8e-13

Best Hits

KEGG orthology group: K01420, CRP/FNR family transcriptional regulator, anaerobic regulatory protein (inferred from 44% identity to psu:Psesu_0364)

Predicted SEED Role

"transcriptional regulator, Crp/Fnr family" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2AI30 at UniProt or InterPro

Protein Sequence (244 amino acids)

>ABZR86_RS01755 helix-turn-helix domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MSVAHAIETPSPGPLHPARCNGCAHLPACQAAGYGRSELRGLQCIAEPAGLLRDGEYLYR
PLTPFHAVYAVQAGMAKSVAVDRAGRERVLAFHLPGELFGLDALWLGQHDNAAVALGRTQ
CCRFPYAALRELASRQVEVQTHLLYAMSRQLHRQHLDAADGSAEQRMAAFLVDLHARREA
LGCSGAALPLPMSRADIGNHLRLATETVSRLLARFRDAGLLRVTRSGVELLDMDGLRHVG
WGEP