Protein Info for ABZR86_RS01690 in Dyella japonica UNC79MFTsu3.2

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 PF00356: LacI" amino acids 32 to 77 (46 residues), 55.4 bits, see alignment 8.6e-19 PF00532: Peripla_BP_1" amino acids 91 to 341 (251 residues), 120 bits, see alignment E=2.8e-38 PF13407: Peripla_BP_4" amino acids 174 to 333 (160 residues), 51.3 bits, see alignment E=2.5e-17 PF13377: Peripla_BP_3" amino acids 193 to 354 (162 residues), 153.1 bits, see alignment E=1.5e-48

Best Hits

Swiss-Prot: 43% identical to CYTR_ECOLI: HTH-type transcriptional repressor CytR (cytR) from Escherichia coli (strain K12)

KEGG orthology group: K05499, LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG (inferred from 57% identity to cak:Caul_0416)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2AGE2 at UniProt or InterPro

Protein Sequence (359 amino acids)

>ABZR86_RS01690 LacI family DNA-binding transcriptional regulator (Dyella japonica UNC79MFTsu3.2)
MSSRGSAKGQAGRARKDGKRAQAEAQPARVSTVKEIAAIAKVSVATVSRALQRPEVVSER
TRQRIHEVVKRLGYTPNALARNLRTARTRLIVALLPDIANPFFSEVIRGIEQVAHENGYS
VLLGETQSSQVREQAYADMVAARQADGIITMSPRVPSIPIQGRLPVVNACEYVKDGQISS
VYIDNVAAAGVAVDYLAMLGHREIAFVAGPPSSPICVDREQGYRLALQRAELPANPGLVV
TGDFSIEAGERAVEQLLAQGQPFTALFCSNDEMAIGALRALRSHGLRVPEDVSVVGFDDI
RFARYTSPPLTTIVQPKNALGREAMSMMLELLNDAEVPPRKRVLTADLVVRGSTMPRRK