Protein Info for ABZR86_RS01380 in Dyella japonica UNC79MFTsu3.2

Annotation: glycoside hydrolase family 2 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 882 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00703: Glyco_hydro_2" amino acids 234 to 342 (109 residues), 52.5 bits, see alignment E=1.2e-17 PF17786: Mannosidase_ig" amino acids 708 to 793 (86 residues), 64.1 bits, see alignment E=2.2e-21 PF17753: Ig_mannosidase" amino acids 798 to 874 (77 residues), 59.8 bits, see alignment E=2.5e-20

Best Hits

KEGG orthology group: K01192, beta-mannosidase [EC: 3.2.1.25] (inferred from 62% identity to xal:XALc_2220)

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2AR81 at UniProt or InterPro

Protein Sequence (882 amino acids)

>ABZR86_RS01380 glycoside hydrolase family 2 protein (Dyella japonica UNC79MFTsu3.2)
MQRSATFPYWSALAVSLILAGPATAAQLSAQSLEQGWQFHIAPKSAEAKTHPEAAEWRAA
AVPGSVQTDLLAAGVITDPFYRDNEARLQWIGLADWDYRLAFKVDPATLKRGHVELVFDG
LDTFADVTLNGRKLVSADNMFRRWRVPVKGMLRSGENKLEVHLHSPIARLQPWLLKQPYA
LPGEFDSAFGDEPKGKQTANYIRKANYQYGWDWGPRYVTLGIWQPVRLESWDEVRLSDFH
IAQQHVDADLAQLQAETSVQADQPGKARLTVSWSDPDGSHQQASQEVELRKGDNALSLPI
RIEHPRRWWPTGYGAQDMYRFEVTLSRDGDTLATASRATGLRSVELRRDKDQWGRGFAFV
VNGVPVFAKGANLIPFDSFPNRVTPERMAQILRSAHDANMNMLRMWGGGHYQSDAFYEEA
DKLGLMIWQDFMFGGAIPPYDEAYRENTRIEAVEQVRRLRDHPSIVLWCGNNEVQTGWEA
WPDRKALRQSLAPEEVARIENGMKTLFGETLRSVVRENAPDVPYWASSPSTDYEGAANQL
TDGDYHSWSVWSGSKPIEQYLGETPRFQSEYGLQSFPVMATVRAFAEERDLEPNSPVMRA
HQKFANGDGNDRLLLYIRKYYGEPKDFESFVYLSQVMQAEGIELAAEHLRSVRPQAMGSL
YWQLNDVWPGASWSSVDYFGRWKALQFHARRFYAPVRVVAIHNDGHSDVFVVSDRTAPFQ
ATLRSRVMSMDGKVLRERKQALKVEPLASTKVASPTDAELLRKADPAASFAVYELLDDKG
AVLSRHLLFVKPPIELKLPDPDLKAELRDNGQGGVLVLSARHLAREVWVDFGTLDATPDD
NAFSLLPGETRELRVVSEAGIDALRGALRVRSLAGATKGDAK