Protein Info for ABZR86_RS01260 in Dyella japonica UNC79MFTsu3.2

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 33 to 50 (18 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 97 to 114 (18 residues), see Phobius details amino acids 126 to 147 (22 residues), see Phobius details amino acids 159 to 180 (22 residues), see Phobius details amino acids 190 to 207 (18 residues), see Phobius details amino acids 218 to 235 (18 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 281 to 301 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 320 to 487 (168 residues), 136.4 bits, see alignment E=3.9e-44 PF00990: GGDEF" amino acids 323 to 484 (162 residues), 143.5 bits, see alignment E=2.6e-46

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2AQJ1 at UniProt or InterPro

Protein Sequence (497 amino acids)

>ABZR86_RS01260 GGDEF domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MNMQALAPRLYAPLLAAHFAVLATEPPRVLSWSYALVLAVLGLTLILGIRRIGLSLPHNR
PLWSLLLAALFSQGAAFVLLFVDSLANPQGTLVAFDPTFYFCMSSLLLTLAATYDPVPPV
YRWTGLLDAALAVFIALMFYGLVRALVAGAEAQPENARAIMWMFDGMALFVAVFASLRLL
GARRRDERRFFVVLAAFAWIELFAPAAHNRFVLSSESYLPEFLLSVPFALLGLLLSRRRG
DWLRGYRPSTRARYLAGSISPFVLSLALCLLAFGYLHRIPAVAVGALVAGIASYALRAAL
MLGKRLSSEDELKRLHHGLRRAALRDDLTQLLNRRGFYRALDREWERARRVHVPLAVAML
DIDHFKAFNDTYGHLAGDQCLASVAQALAGEAASMPGVTVARAGGEEFVVLISGYLPHAA
GALLEQLRERVEALRILHVRGVRGFVTVSAGIASSELARYGDAEAMLSAADAALYTAKRA
GRNQVAWAEVPGTEALS