Protein Info for ABZR86_RS01205 in Dyella japonica UNC79MFTsu3.2

Updated annotation (from data): D-galactanolactonase
Rationale: Specifically important for galactose utilization. It is not certain whether the galactose dehydrogenase (N515DRAFT_1230) forms the 1,5-lactone or the 1,4-lactone.
Original annotation: SMP-30/gluconolactonase/LRE family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 54% identical to ARALA_AZOBR: L-arabinolactonase (araB) from Azospirillum brasilense

KEGG orthology group: K13874, L-arabinonolactonase [EC: 3.1.1.15] (inferred from 56% identity to hse:Hsero_1044)

Predicted SEED Role

"L-arabinolactonase (EC 3.1.1.15)" in subsystem L-Arabinose utilization (EC 3.1.1.15)

MetaCyc Pathways

L-arabinose degradation III (5/6 steps found)
L-arabinose degradation IV (5/8 steps found)
L-arabinose degradation V (3/6 steps found)
superpathway of pentose and pentitol degradation (12/42 steps found)

KEGG Metabolic Maps

Ascorbate and aldarate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2AUG6 at UniProt or InterPro

Protein Sequence (300 amino acids)

>ABZR86_RS01205 D-galactanolactonase (Dyella japonica UNC79MFTsu3.2)
MNARVVHHPANTLGEGILWCEREQALYWTDIQAATLWRHRPADGATRSWEMPERLGCLAL
CEADGWLLLGLATRLAFFRPEDDLLLPLVSVEPDLPTRLNDGACDRQGRFVFGTLHEPAA
GETRQPIGAFYRLNADLTLERLNLPGIGISNSVAFSPDGRTMYFCDSPSRVIQCCDYGDR
CGEPRVFARVDDERGEPDGSAVDAQGCLWNAQWGLGRVVRYAPDGRVDRIVEVPATQPTR
PAFGDSPLDTLYITSARDGLSSAALATQPLAGALFAADAGASGLPEPRFRGAPPGFGRSS