Protein Info for ABZR86_RS00980 in Dyella japonica UNC79MFTsu3.2

Annotation: signal peptidase II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 68 to 87 (20 residues), see Phobius details amino acids 97 to 113 (17 residues), see Phobius details amino acids 133 to 157 (25 residues), see Phobius details TIGR00077: signal peptidase II" amino acids 5 to 158 (154 residues), 146.3 bits, see alignment E=4e-47 PF01252: Peptidase_A8" amino acids 14 to 156 (143 residues), 142.8 bits, see alignment E=4.4e-46

Best Hits

Swiss-Prot: 55% identical to LSPA_PSESM: Lipoprotein signal peptidase (lspA) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

KEGG orthology group: K03101, signal peptidase II [EC: 3.4.23.36] (inferred from 55% identity to psp:PSPPH_0722)

Predicted SEED Role

"Lipoprotein signal peptidase (EC 3.4.23.36)" in subsystem Sex pheromones in Enterococcus faecalis and other Firmicutes or Signal peptidase (EC 3.4.23.36)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.23.36

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2CP43 at UniProt or InterPro

Protein Sequence (166 amino acids)

>ABZR86_RS00980 signal peptidase II (Dyella japonica UNC79MFTsu3.2)
MSNQRNALSWLWLSALVIALDQASKWWALSALQPAGVQHVIIPGFLNWTLAFNTGAAFSF
LADSAGWQRWFFVGLAVLISGALLVWLKRTSRDDWRTALPLGLIIGGALGNLIDRLHAAQ
VTDFIQVHYQDWYYPVFNIADCGITVGAVLLIAFGLFTGKQAGGVR