Protein Info for ABZR86_RS00585 in Dyella japonica UNC79MFTsu3.2

Annotation: molecular chaperone HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 PF13589: HATPase_c_3" amino acids 28 to 169 (142 residues), 35.2 bits, see alignment E=1.8e-12 PF00183: HSP90" amino acids 219 to 618 (400 residues), 430 bits, see alignment E=2.5e-132

Best Hits

Swiss-Prot: 58% identical to HTPG_BORBR: Chaperone protein HtpG (htpG) from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 77% identity to psu:Psesu_3037)

MetaCyc: 55% identical to chaperone protein HtpG (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2CEY6 at UniProt or InterPro

Protein Sequence (620 amino acids)

>ABZR86_RS00585 molecular chaperone HtpG (Dyella japonica UNC79MFTsu3.2)
MTTETRKFEAEVAQVLHLVTHSLYSHKEIFLRELISNASDACDKLRFESIAQPELLAGDG
ELHIDVSWDPQARTVTVRDNGVGMNVDEVVANIGTIASSGTRRFLDAMSAEQKTDARLIG
QFGVGFYSAFVVADRVTVLTRRAGAPAGEGVKWESDGKGEYSLERVELAERGTAVILHLK
ADEDEFLQPWTLKSLITRYSDHVAFPIRLPVEQDGKPGEEWETVNAASALWTKPKSEISD
EDYQSFYKSLGHDFNDALAWAHNRVEGSQSFTTLLYIPAQPPFELMMGGRDERKGLKLYI
KRVFIMDAAEELLPNYLRFVRGVVDADDLPLNVSREILQQNRQLERIKSACVKRVLDLLE
KMARDEPEKFATFYKAFGNTLKEGIAEDHANRERIAKLLRFASTKGEGAAQAVSLDDYIL
RMAPGQDIIWYITADSHAAAIGSPQLEAFKAKGIEVLLMSDRIDEWMLGSLNEYAGKKLQ
NVAKGELPLDEADKQRQQEASAAAAPLLDKLKSLLGERVKDVRVSARLTDSPSCLALSDY
EMAPHLARLLREAGHDMPESKPVLEINPRHALLQRVEAEGDETRAGDLANLLLEQAEIAA
GAQLPDPAAFVQRMNRVLLG