Protein Info for ABZR86_RS00480 in Dyella japonica UNC79MFTsu3.2

Annotation: glutathione peroxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00255: GSHPx
  • amino acids 5 to 111 (107 residues), 145.6 bits, E=2e-47

Best Hits

Swiss-Prot: 54% identical to GPO_LACLM: Glutathione peroxidase (gpo) from Lactococcus lactis subsp. cremoris (strain MG1363)

KEGG orthology group: K00432, glutathione peroxidase [EC: 1.11.1.9] (inferred from 71% identity to axy:AXYL_02866)

MetaCyc: 53% identical to hydroperoxy fatty acid reductase 1 (Synechocystis sp. PCC 6803)
RXN-13944 [EC: 1.11.1.22]; 1.11.1.- [EC: 1.11.1.22]

Predicted SEED Role

"Glutathione peroxidase family protein"

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• glutathione-peroxide redox reactions (2/3 steps found)

KEGG Metabolic Maps

• Arachidonic acid metabolism
• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.11.1.22 or 1.11.1.9

Sequence Analysis Tools

See A0A1I2CCN0 at UniProt or InterPro

Protein Sequence (161 amino acids)

>ABZR86_RS00480 glutathione peroxidase (Dyella japonica UNC79MFTsu3.2)
MTTAYDFSARDIDGNERSLAEWRGKTLLIVNVASKCGFTPQYEGLEQLWRAGRDKDLVVL
GFPCDQFGHQEPGDEAEIKNFCSLSYDVTFPMFAKIEVNGDGTHPLYQWLKSEGKGILGS
ESIKWNFTKFLVGPDGQVVKRYAPTDTPARIGKDVKVQLAG