Protein Info for ABIE53_006556 in Paraburkholderia graminis OAS925

Annotation: MFS family permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 45 to 68 (24 residues), see Phobius details amino acids 74 to 94 (21 residues), see Phobius details amino acids 106 to 123 (18 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 162 to 186 (25 residues), see Phobius details amino acids 192 to 214 (23 residues), see Phobius details amino acids 245 to 265 (21 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 314 to 332 (19 residues), see Phobius details amino acids 340 to 364 (25 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details amino acids 401 to 423 (23 residues), see Phobius details PF07690: MFS_1" amino acids 43 to 299 (257 residues), 125.3 bits, see alignment E=4.1e-40 amino acids 298 to 427 (130 residues), 41.6 bits, see alignment E=1.1e-14 PF12832: MFS_1_like" amino acids 67 to 388 (322 residues), 29.6 bits, see alignment E=5.7e-11 PF00083: Sugar_tr" amino acids 73 to 227 (155 residues), 63.8 bits, see alignment E=2.2e-21 amino acids 280 to 427 (148 residues), 28.4 bits, see alignment E=1.2e-10

Best Hits

Swiss-Prot: 40% identical to MMLH_CUPNJ: Probable 4-methylmuconolactone transporter (mmlH) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: None (inferred from 96% identity to bug:BC1001_5552)

Predicted SEED Role

"Sialic acid transporter (permease) NanT" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>ABIE53_006556 MFS family permease (Paraburkholderia graminis OAS925)
METKAQLTADAERYGASDAGKGPFAWYRRISAAEKRAFWSCKIGYVLDAMDTQFLSFVIP
TLIATWGITRGDAGLIGTVTLLSSAVGGWAAGVLSDRVGRVKTLQITILWFAVFTLACAL
AQNFSQLLWARGLMGLGFGGEWTAGAVLIGEVIRARDRGKAVGLVQAGWAIGWGVSTLLF
MAVFSLVPADYAWRVLFAIGIAPAPFVIWIRRFVEEPEVHRRQKEAQDAAQARPALLDIF
RGDIVWTTLRASILATGVQGGYYAVTTWLPTYLKTERHLSVIGTGSYLGVVIVGSYCGYL
TGAYVSDRIGRKRAFIAFALASCAIASIYTQLPLDNFSMLVLGFPLGFCASGIFSGMGAF
LTELFPTRIRGSGQGFCYNFGRAVGATFPFLIGYVSQTMTLGHAIGAFAAAAYGIVILAA
LTLPETRGRALDD