Protein Info for ABIE53_006507 in Paraburkholderia graminis OAS925

Annotation: ACS family glucarate transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details transmembrane" amino acids 58 to 80 (23 residues), see Phobius details amino acids 88 to 131 (44 residues), see Phobius details amino acids 155 to 174 (20 residues), see Phobius details amino acids 181 to 200 (20 residues), see Phobius details amino acids 257 to 280 (24 residues), see Phobius details amino acids 289 to 314 (26 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 387 to 410 (24 residues), see Phobius details amino acids 416 to 437 (22 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 319 (294 residues), 162.3 bits, see alignment E=8e-52 TIGR00893: D-galactonate transporter" amino acids 29 to 438 (410 residues), 468.9 bits, see alignment E=6.5e-145

Best Hits

Swiss-Prot: 60% identical to GUDP_ECOLI: Probable glucarate transporter (gudP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to bug:BC1001_5597)

MetaCyc: 60% identical to galactarate/D-glucarate transporter GudP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-203; TRANS-RXN0-204; TRANS-RXN0-523

Predicted SEED Role

"D-glucarate permease" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>ABIE53_006507 ACS family glucarate transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MEMSRTASSANVAKRTKVRYAILLLIFVITTFNYADRATLSVTGSAMRAEFGFDAIRMGY
IFSAFSWAYVASQLPAGWLLDRFGARRVYAASIFFWSLFTLLQSSIGLLGSAAAAVTGLF
VLRFAMGAAESPAFPANAKVVASWFPTKERGTASAIFNSAQYFAAVIFTPLMAWLTHAFG
WHMVYVVMGVAGLLLALTWLKVMKHPADHPGVSASELEYIEQGGGVINGHQKTGPADVEK
AGGWSLVRQLLTNRMLVGVYLAQYCINVLTYFFLTWFPIYLVQARHMTILQAGLVASLPA
ICGFSGGVLGGILSDSLIRRGHSLTVARKVPIVGGMLLSVSIIGCNYVSTDWIVVALMSL
AFFGKGIGALGWAVVADTSPKEALGLSGGIFNMFGNVAGIVTPIVIGYLVAQSGSFNGAL
VFVGANALLTVFSYLVIVKDIKRVELRPR