Protein Info for ABIE53_006427 in Paraburkholderia graminis OAS925

Annotation: isoquinoline 1-oxidoreductase beta subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details PF20256: MoCoBD_2" amino acids 80 to 229 (150 residues), 56.1 bits, see alignment E=4.5e-19 amino acids 603 to 698 (96 residues), 73.3 bits, see alignment E=2.5e-24 PF02738: MoCoBD_1" amino acids 347 to 577 (231 residues), 127.9 bits, see alignment E=3.6e-41

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 96% identity to bug:BC1001_5670)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (750 amino acids)

>ABIE53_006427 isoquinoline 1-oxidoreductase beta subunit (Paraburkholderia graminis OAS925)
MSQGLLDAYKGAKRPQAEADEARGVSRRTFLKFGVSVGAAAGGGLLLGFSLPAVSQDQKS
GKSVIGGDANEAPQNGVFAPNAFIQIDTAGKVTLVIPKVEMGQGVYTSIPMLIAEELEVP
LDTVTLDHAPPDEKLFTDPLLGGQLTGGSTSIRYAWEPMRRAGATARTLLVSAAAQQWQV
DAASCHAQAGQVIHAASNRSIGYGQLVEAAAKLPAPQNVPLKNPKDFKIIGTAVKRLDSP
EKVDGTAMFGLDVRVPDMVYAAIANCPVFGGTLASVDDTNAKKIPGVRQVVKIDNAVAVI
GDHTWAAKRGLQALDIKWNEGADAKLSMKQIVDDLANASQRNGAVARKDGDVVHAFSNAK
TRVDAIYQQPFLAHATMEPINCTVHVRADSCEVWLGSQVPTRVRDAAMAVTGLPADKIIV
HNHLIGGGFGRRLEFDMVTQAVKIAKQVSTPVKVLWTREEDIQHDMYRPYYYDKISAGLD
ANGKPLAWQHRIVGSSILARFAPPAFKNGLDPDAVEVASDLPYDLPNQLVDYVRQEPHAI
PTAFWRGVGPTRSTFVVESFIDELAAEAKVDPVKYRRDLLGKTPRALNVLNVAAQAADWG
SAVPKGQGRGVSVMHAFGSYFAIIVDVAVEQGEVAVKRVVCAVDCGMVVNPNTVEAQVQG
GIIFGITGALYSEITIKDGRVQQNNFTDYRMLRIDQTPPIDVHIVKSSEAPGGIGEPGTA
ALAPALTNAIFAATGKRLRHLPVGSQLQTA