Protein Info for ABIE53_006421 in Paraburkholderia graminis OAS925

Annotation: Ca2+:H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 signal peptide" amino acids 7 to 11 (5 residues), see Phobius details transmembrane" amino acids 12 to 27 (16 residues), see Phobius details amino acids 34 to 54 (21 residues), see Phobius details amino acids 65 to 89 (25 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 247 to 269 (23 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details amino acids 310 to 332 (23 residues), see Phobius details amino acids 340 to 359 (20 residues), see Phobius details PF01699: Na_Ca_ex" amino acids 35 to 187 (153 residues), 69.5 bits, see alignment E=1.6e-23 amino acids 218 to 358 (141 residues), 48.4 bits, see alignment E=5.2e-17

Best Hits

Swiss-Prot: 51% identical to Y4HA_SINFN: Putative ionic transporter y4hA (NGR_a03490) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K07300, Ca2+:H+ antiporter (inferred from 93% identity to bug:BC1001_5680)

Predicted SEED Role

"Calcium/proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>ABIE53_006421 Ca2+:H+ antiporter (Paraburkholderia graminis OAS925)
MTMSATVLPRWTLAVPFVAWIVLGASYALPGNGLLLALVGIALCAAVFAAVHHAEVVAHQ
VGEPFGTLVLAIAVTVIEVALIVSVMLTAGPEKAGLARDTVFAAVMIVCNGIVGMCLLVG
GIRHREQDFQIRGAAAALAVLASLSVLTLVMPNYTTTNVGPMLSSSQLAFAGVSSLVLYG
VFVFVQTVRHRDYFLADVSDEDVHAAPPGARLALTSGGLLLVCLVAVVLLAKVLSPVVET
AVENAGAPAAVVGIVIAALVLLPEGLAAVRAARADRLQNSLNLALGSALASIGLTIPTVA
AVFLTTGQPLVLGINGKETVLLVLTLLVSTLTISTGRTTILQGAVHLSLFAAYLFLSFAP