Protein Info for ABIE53_006212 in Paraburkholderia graminis OAS925

Annotation: heterotetrameric sarcosine oxidase gamma subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 826 PF01266: DAO" amino acids 10 to 375 (366 residues), 251.4 bits, see alignment E=7.6e-78 PF16350: FAO_M" amino acids 379 to 433 (55 residues), 75.4 bits, see alignment 1.3e-24 PF01571: GCV_T" amino acids 435 to 706 (272 residues), 274.8 bits, see alignment E=2.5e-85 PF08669: GCV_T_C" amino acids 732 to 818 (87 residues), 63 bits, see alignment E=7.9e-21

Best Hits

KEGG orthology group: None (inferred from 92% identity to bug:BC1001_5775)

Predicted SEED Role

"Sarcosine dehydrogenase (EC 1.5.99.1)" (EC 1.5.99.1)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (826 amino acids)

>ABIE53_006212 heterotetrameric sarcosine oxidase gamma subunit (Paraburkholderia graminis OAS925)
MSTPLPPQTRVVIIGGGIIGCSVAYHLTRLGWADVILLEQGQLSCGTTWHAAGLVGQLRA
QESMTKLIRYSTALYAELEADTGLATGWKQCGSLSVARTAERMTQLKRTAAVARAYGVTC
EVIGAREAGDLWPVMRTDDLLGAVWLPGDGKANPTDLTQALARGARMRGARIVENTRVTA
IHARDAHGSREATGVAWRNKDGDEGSISADIVVNCAGQWAKAVGRLCGVTVPLHSAEHYY
IVTDRIEGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPDAKPWGMNGIPENFEFQLLPD
DWNQFEILMTNALQRVPALETAQVRQFYNGPESFTPDNNFMLGEAPELRRFFVGAGFNSM
GIASAGGAGMALAEWIVAGEPTMDLWPVDIRRFARFNGNDAWLHDRVKETLGLHYAMPWP
NRELDSARPLRRSPLYALLREDGACFGSKMGWERANFFAPTPGEARVDYTFGQPDWLRAS
GAEHRACREGVALFDMTSFSKFLVKGRDAQSVLQSLVTNDVDVPPGTAVYTGMLNERGNY
ESDFTLTRIAADQYLLVTGTAQTTRDFDMIERAIPRDKHCVLVDVTSQYAVLAVMGPRSR
ELLQSVSKADWRNEAFAFGQSREVDIGYATVRATRLTYVGELGWELYVPVEFAVGVYEAL
REAGKAFGLANAGYYAIDSLRIEKGYRAWGRELTPDTNPFEAGLAFACKLDKEIPFRGRD
ALLKLRDEPLRRRMVVLSADGAADRMLWGGEAILRDGKPVGFVSSAAFGHTLGCPVAMGY
VNNPDGAADAAYLTSGAYAIDVAGESLPATLHLKAPYDPRGERVRA