Protein Info for ABIE53_006125 in Paraburkholderia graminis OAS925

Annotation: glycine betaine/proline transport system substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR03414: choline ABC transporter, periplasmic binding protein" amino acids 25 to 314 (290 residues), 450.8 bits, see alignment E=9.8e-140 PF04069: OpuAC" amino acids 33 to 285 (253 residues), 203.4 bits, see alignment E=2.5e-64

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 97% identity to bgf:BC1003_5889)

Predicted SEED Role

"L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>ABIE53_006125 glycine betaine/proline transport system substrate-binding protein (Paraburkholderia graminis OAS925)
MMNKLFKQAMSGVALLCAAASFASAAEPQSCMQVNMAGPGWTDIDATNAMTGVVLKALGY
KQKVANLSVPITYQGLKKGQIDVFLGNWMPAQAPVVKPFEEEKSIVVVHPNLSNAKFTLA
VPDYVAAAGVHSFADLAKNADKFDSKIYGIEPGAPANQNIKKMVDDKAFGLDSWKVVESS
ETGMLTQVERAVREKKWIVFLAWEPHVMNTKFKLSYLDGGDKYFGPNYGGATVNTVARSG
YAEQCPNVGRLFRQLTFNVDLENGVITEVLEKKTSVDVAATEALKRHPDLLKSWLDGVST
ANGANGLQAVQTALGVK