Protein Info for ABIE53_006102 in Paraburkholderia graminis OAS925

Annotation: erythritol transport system substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 30 to 281 (252 residues), 186.8 bits, see alignment E=8.3e-59 PF00532: Peripla_BP_1" amino acids 30 to 256 (227 residues), 68.8 bits, see alignment E=8.4e-23 PF13377: Peripla_BP_3" amino acids 188 to 300 (113 residues), 31.4 bits, see alignment E=3.1e-11

Best Hits

KEGG orthology group: K10439, ribose transport system substrate-binding protein (inferred from 72% identity to smd:Smed_3770)

MetaCyc: 48% identical to putative erythritol ABC transporter substrate-binding protein (Brucella abortus 2308)
7.5.2.-

Predicted SEED Role

"Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>ABIE53_006102 erythritol transport system substrate-binding protein (Paraburkholderia graminis OAS925)
MKASKRWVALAAATLTLFTATGTAQAANLIAIITPSHDNPFFKAEADTANARAKALGYDT
IVLVHDDDANKQSNLVDTAIARGAKAIILDNAGSEASIAAVRKAKAAGIPSFLIDREINA
TGIAVSQIVSNNYQGAQLGGRAFVKALGEKGNYVELVGREADINAGIRSKGYHDVIDQFP
NMKMVERQSANWSQTEAYRVMETILQSHPDIKGVIAGNDTMAMGASAALKAAKRSDVIVV
GFDGSNDVRDAIMRNDIRATVLQPAALAATEAVEQADKYMKTGSTGKPEKQLINCSLITK
ANAGKLDMFALR