Protein Info for ABIE53_006083 in Paraburkholderia graminis OAS925

Annotation: tyrosine-protein kinase Etk/Wzc

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 447 to 468 (22 residues), see Phobius details PF02706: Wzz" amino acids 16 to 109 (94 residues), 62.2 bits, see alignment E=1.2e-20 TIGR01005: exopolysaccharide transport protein family" amino acids 16 to 744 (729 residues), 640.6 bits, see alignment E=3.4e-196 PF13807: GNVR" amino acids 389 to 468 (80 residues), 92 bits, see alignment E=4.5e-30 TIGR01007: capsular exopolysaccharide family" amino acids 526 to 719 (194 residues), 129.9 bits, see alignment E=9.5e-42 PF01656: CbiA" amino acids 550 to 719 (170 residues), 30.4 bits, see alignment E=8.3e-11 PF13614: AAA_31" amino acids 556 to 668 (113 residues), 41.8 bits, see alignment E=2.9e-14

Best Hits

Swiss-Prot: 56% identical to EPSB_RALSL: Putative tyrosine-protein kinase EpsB (epsB) from Ralstonia solanacearum

KEGG orthology group: K00903, protein-tyrosine kinase [EC: 2.7.10.-] (inferred from 61% identity to cti:RALTA_A1638)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.- or 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (750 amino acids)

>ABIE53_006083 tyrosine-protein kinase Etk/Wzc (Paraburkholderia graminis OAS925)
MNEFSPKSQAAGSGQNDVNLVRYVDVVLANRWLVLAITSMVLAIGVAYSFLAPPVYQSDI
LLQVEQESPTNTKSLLGDVSSLFDVKTETTAQIEVLRSRMVVGNAVDNLRLYISAEPKRF
PLIGNWIARWNKSLSQPGLLGVGGFAWGNESIDVGTFDVPEDLEGDDFKLTSLGGDRYVV
DQKQLDAPIYGRVGETIVSNESTGKITLRVQALNANPGTEFVLVRNARLKTLENLQDKLF
IVEKGKQSGIIGASLTGTDRQLTAKILNNIGDEYVAANIARKAAEAEKSLAFLSDLLPQL
KSELEESERNYNALRIKRGTFDISEEGKTYLRESVELQASALALKQKRSELTALFTSEHP
SVRAVDQQLASLSAKEAAVSQRMTSLPELEQESLRLMRDVRVNNDLYVGMLNNMQQLKLV
RAGKVGTVRLLDRSLVPKEPIKPNKPLLIAASAVLGLFLGIAATFMRHILRGGVTNPQDI
EQETGLTVYATVPVSRTQATLEHDSPERSEGLLLLASHSPGDPSVESLRSLRIVLQLSML
EAGNNRVLLTGPSEQIGKSFLCANLAAVMTGSGKRVLLIDADLRRGHLNDYFGKESQPGL
ADVLTSNATLDEALQRNVAPGLDFLPNGTTPSDPAELLMGDAMARLLESVGDSYDMVLID
TPPVLAVSDAAVVAHRCGTVFLATRFGTTSVDEVRESVKQLRHANVEVKGVIFNAFHPAA
YRYSLGSHAGRNRYLSYQYATASSDSKSNS