Protein Info for ABIE53_006053 in Paraburkholderia graminis OAS925

Annotation: phenylpropionate dioxygenase-like ring-hydroxylating dioxygenase large terminal subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00355: Rieske
  • amino acids 16 to 95 (80 residues), 74.9 bits, E=3.9e-25
• PF19112: VanA_C
  • amino acids 154 to 347 (194 residues), 141.9 bits, E=2.8e-45

Best Hits

KEGG orthology group: K03862, vanillate monooxygenase [EC: 1.14.13.82] (inferred from 90% identity to bgf:BC1003_3627)

Predicted SEED Role

"FIG00459198: hypothetical protein"

MetaCyc Pathways

• vanillin and vanillate degradation II (1/2 steps found)

KEGG Metabolic Maps

• 2,4-Dichlorobenzoate degradation

Isozymes

Compare fitness of predicted isozymes for: 1.14.13.82

Use Curated BLAST to search for 1.14.13.82

Protein Sequence (361 amino acids)

>ABIE53_006053 phenylpropionate dioxygenase-like ring-hydroxylating dioxygenase large terminal subunit (Paraburkholderia graminis OAS925)
MPRSDWRLAVPYLLNAWYVAALSSEVTADAPLARTLLDEPVVLYRVAGGHAVALADRCPH
RFAPLSRGRVVDGALECPYHGLRFGAEGRCVFNPHGDGRVPARAEARHYPVRERYGAIWL
WPGDPQRASDTPLPAFDYLDPQENFTSERYLHTHANYQLSADNLLDLSHFQYLHPETLGS
EQMASGAVRATVAGNTVSVRREMKGEYLRPMLTQSFNLLYGERADRELDVQWIPPGLLTI
VVRICESGLPETTREAVSAHWLTPETAASSHYFFAFGLPRAIGEHGAELVSRTAQSLLAP
FRDEDIPMLEAQQRMIGERDFWSLRPAMLPIDAGAVHARRIMERLIADEARQGVSTAGEV
L