Protein Info for ABIE53_006009 in Paraburkholderia graminis OAS925

Annotation: two-component system NtrC family sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 PF00989: PAS" amino acids 7 to 55 (49 residues), 35.3 bits, see alignment 2.1e-12 TIGR00229: PAS domain S-box protein" amino acids 7 to 74 (68 residues), 27.8 bits, see alignment E=1.1e-10 PF08448: PAS_4" amino acids 11 to 129 (119 residues), 31.6 bits, see alignment E=3.4e-11 PF02518: HATPase_c" amino acids 324 to 440 (117 residues), 90.6 bits, see alignment E=1.9e-29

Best Hits

KEGG orthology group: None (inferred from 91% identity to bug:BC1001_3610)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (471 amino acids)

>ABIE53_006009 two-component system NtrC family sensor kinase (Paraburkholderia graminis OAS925)
MKTSLSEAIVERVNCGVFTVDRDLRILTWNRFMQSHSGRSAESVVGQNLLDVFPELPRQW
LSRKIEGVFVLGTPAYSSWEHRPYLFRFEHSRPITGTIDAMRQNCNFIPIENSRGEVVAV
GVAIVDTTDVCIAYGELQDREKAVTNALAELTVRNQQLTSLNDALAHAHQQLLQSEKLAA
IGQLAAGVAHEINNPVGFVLSNLNTLDGYVKTLIRYAADVQRMVSEAAPALKHDIEALAE
QADLDYLLGDAPTLVHESKEGLARVRTIVVDLRDFSRVDSTQVWELADIHRCIESTLNIV
HNEVKYCAHLVREYAEIPFVRCIPSQISQVVLNLVVNAAQAYGGNHEQHGAPRGTITVRT
GMDAADPSRVWFEVADMGCGIPPELLKRIFDPFFTTKPVGQGTGLGLSVTYGIVNAHRGT
ISVASTIGEGTTFRVTLPVDGAQPEDSNTEALAQSGSLDAIALPAQSPAAT