Protein Info for ABIE53_005915 in Paraburkholderia graminis OAS925

Annotation: two-component system chemotaxis response regulator CheB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 transmembrane" amino acids 36 to 58 (23 residues), see Phobius details PF01339: CheB_methylest" amino acids 25 to 201 (177 residues), 182.9 bits, see alignment E=2.3e-58

Best Hits

KEGG orthology group: K03412, two-component system, chemotaxis family, response regulator CheB [EC: 3.1.1.61] (inferred from 91% identity to bgf:BC1003_3752)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.61

Use Curated BLAST to search for 3.1.1.61

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (208 amino acids)

>ABIE53_005915 two-component system chemotaxis response regulator CheB (Paraburkholderia graminis OAS925)
MPRSITQPDVDAARDAQDARACELVVIGGSAGGMEVINLLLAALPASFAPAVMIVMHLPP
DPPSYLVHALAHRCGLPVIEPDAGEQIMPGRVHVAPPGYHMLVEVDRTVALSTDAAVRFS
RPSIDVLFESAADVYREHLLALLLSGANDDGVNGLQRVRALGGVAWVQDPATAMSSEMPR
TAIERGAADYIYSPETMARRLAAWPASL