Protein Info for ABIE53_005903 in Paraburkholderia graminis OAS925

Annotation: propionate catabolism operon transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 678 TIGR02329: propionate catabolism operon regulatory protein PrpR" amino acids 15 to 675 (661 residues), 559.9 bits, see alignment E=2.8e-172 PF06506: PrpR_N" amino acids 39 to 204 (166 residues), 146.6 bits, see alignment E=2.5e-46 PF08448: PAS_4" amino acids 217 to 319 (103 residues), 24.3 bits, see alignment E=1.4e-08 PF00158: Sigma54_activat" amino acids 348 to 516 (169 residues), 228.7 bits, see alignment E=1.6e-71 PF14532: Sigma54_activ_2" amino acids 349 to 520 (172 residues), 71 bits, see alignment E=5.7e-23 PF07728: AAA_5" amino acids 372 to 491 (120 residues), 27.9 bits, see alignment E=9.9e-10 PF02954: HTH_8" amino acids 646 to 674 (29 residues), 34.9 bits, see alignment (E = 4.6e-12)

Best Hits

KEGG orthology group: K02688, transcriptional regulator, propionate catabolism operon regulatory protein (inferred from 84% identity to bpy:Bphyt_5404)

Predicted SEED Role

"Propionate catabolism operon regulatory protein PrpR" in subsystem Methylcitrate cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (678 amino acids)

>ABIE53_005903 propionate catabolism operon transcriptional regulator (Paraburkholderia graminis OAS925)
MSTFTPTFVNADPGRPGIALVSISRLQSLCETIAPRYAGRARFFSVREGYGAAVTALQAH
VDAGSVDVVLAAGSNGAYLRENLSVPVVMVKVNGFDVLSAITRATAARPGAPIGLVLHET
ISHELADLGGWLNVRLTQRAYRSVDEVRTAVNDLAAEGCRVIIGPGMACDLAQQAGLDSV
FLYSLGAVEEAFERSVELARVSRQKESKRVRLNTIVAHLRDGVAAFDDAGQLEAVNPAML
DLLGLTGDRHGDRHRDNDRDRDVPAELARTLGPWLREAAERGDAADERIEQIGERSLIVN
CVPILEQGARSGSVVTVQDALVAQRIDRSLRTSQRPKHLVARHRLDDLVGESAALERVRR
LARAGAAHDATVLLTGESGTGKELVAQGIHNASRRRGNPFVAFNCAALPEGLIESELFGH
EEGAFTGARRGGKPGLFEIAHTGTIFLDEIGEMPAALQSRLLRVLQEREVMKLGSGRATP
IDVRVIAATHRDLHALVERGAFRADLYFRLNLLQIELPPLRERRADVVPLARHLLSRGAR
QYGLSEASIGRVLQFLAPLFERYAWPGNVRELENLLTRAAIYLGDAAGDLDRDIGPDLLA
LFPEFDRMQRENGKDALRIAPNAHAADAASAPAAPRITPTRDDVAKALEQCGGNRAAASR
ALGIGRTTLWRLLKADDA