Protein Info for ABIE53_005845 in Paraburkholderia graminis OAS925

Annotation: MHS family proline/betaine transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 transmembrane" amino acids 19 to 44 (26 residues), see Phobius details amino acids 63 to 84 (22 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details amino acids 162 to 186 (25 residues), see Phobius details amino acids 195 to 216 (22 residues), see Phobius details amino acids 256 to 274 (19 residues), see Phobius details amino acids 293 to 314 (22 residues), see Phobius details amino acids 323 to 342 (20 residues), see Phobius details amino acids 351 to 373 (23 residues), see Phobius details amino acids 385 to 407 (23 residues), see Phobius details amino acids 418 to 437 (20 residues), see Phobius details PF07690: MFS_1" amino acids 59 to 399 (341 residues), 79.8 bits, see alignment E=1.9e-26 PF00083: Sugar_tr" amino acids 65 to 441 (377 residues), 85.4 bits, see alignment E=4.1e-28

Best Hits

KEGG orthology group: None (inferred from 63% identity to bge:BC1002_5741)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (456 amino acids)

>ABIE53_005845 MHS family proline/betaine transporter-like MFS transporter (Paraburkholderia graminis OAS925)
METTLAGARNTATQSNRSIVIAAAASCFGWALDLFDLFILLYVAPVVGKLFFPSDHPTLS
LAGVYASFAVTLLMRPIGSALFGSYADRNGRKRAMQIAVFGVGISTAVFGTLPTIAQAGV
IAPILFVLLRLVQGVFVGGVVASSHTLGTESVPPHWRGAVSGLIGGGGAGIGGLLASIVF
FIASALFPGPQFEVWGWRVMFFAGLITSLLGALLFLRLEESPFWKEQHARKAARKAAVSK
QSSPLRTLFSSEYRRVMIVNVIMTTSSGAGYYLCSGYLPTFLKVVKHLPNGTTSTILMAT
GLLSIAAAIAIGAASDFFGRKKVFIGAGVLRIALLPILYILMTKTDSVPLLAGYTLLLAV
LGGASYAPLLIFLNERFPTAIRASGTGLSWNIGFALGGMMPTFVSLLSANEQQLPATLSW
FLLGVSALFLVGAFIVPETRGNLEASRRSEAGMPGA