Protein Info for ABIE53_005833 in Paraburkholderia graminis OAS925

Annotation: isoquinoline 1-oxidoreductase beta subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 735 PF10518: TAT_signal" amino acids 13 to 30 (18 residues), 23.3 bits, see alignment (E = 6.8e-09) PF20256: MoCoBD_2" amino acids 25 to 200 (176 residues), 69.7 bits, see alignment E=4.7e-23 amino acids 600 to 682 (83 residues), 68.1 bits, see alignment E=1.4e-22 PF02738: MoCoBD_1" amino acids 323 to 558 (236 residues), 109.9 bits, see alignment E=1.7e-35

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 93% identity to bgf:BC1003_2374)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (735 amino acids)

>ABIE53_005833 isoquinoline 1-oxidoreductase beta subunit (Paraburkholderia graminis OAS925)
MTTDLDLPDAVRPSRRTFLKAAGAVAAVGLTIGFEWAGTGRRALAATAPEAAFAPNAFLR
VAPDNSVTVIAKHVEMGQGAYTGIATIVAEELDANWQDVRVESAPADAKRYANLAFGMQG
TGGSSAMANSWMQLREAGAKARAMLVSAAAAQWRTPASELTTRDGSVHHAATNRTATYGS
LASAAARLPVPDKVALKSPKDFRLIGHQAPRVDVPPKTDGTAQFTLDVTFPGMLVALLQR
PPLFGATVRSFDASAAKAVPGVVSVVQVPGGVAVVAKGFWAAKQGRDALKIEWDDSKAEK
RSSDAIMAEYRQLAEQPGASARKDGDATQALAGAAKKISATYSFPYLAHAPMEPLDAVVK
LTADSCEIWAGDQFQTVDQGNAARTAGLAPEQVKIHTLYAGGSFGRRANARSDYIVEAVS
IARALGANGTPVKLQWTREDDIHGGFYRPMYFHKLDAGLSADGKLVGWRHRIVGQSILGG
TPFASAMIKNGIDATSVEGAANMAYAIPNISVELTTTQTGVPVLWWRVVGSSHTAFAVEA
FIDEAAHAAGKDPFVFRRDLLAHEPRMRAVLELAARKAGWDPAKPLPKGRGRGIAVAEAF
KTFVAQVAEVSVDKDGNVKIERVVCAVDCGTPINPDIIAAQMEGGIGFGLGAVLHSAITL
KDGKVEQNNFDGYQVLRIAEMPKVEVHIVPSGEAPTGVGEPGVAPVGPAVANAIFAATGE
RLHSLPFPAAAKKSA