Protein Info for ABIE53_005342 in Paraburkholderia graminis OAS925

Annotation: cytochrome o ubiquinol oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 202 transmembrane" amino acids 26 to 48 (23 residues), see Phobius details amino acids 63 to 86 (24 residues), see Phobius details amino acids 94 to 112 (19 residues), see Phobius details amino acids 132 to 160 (29 residues), see Phobius details amino acids 175 to 199 (25 residues), see Phobius details PF00510: COX3" amino acids 10 to 198 (189 residues), 54.8 bits, see alignment E=6.5e-19 TIGR02842: cytochrome o ubiquinol oxidase, subunit III" amino acids 22 to 201 (180 residues), 271.1 bits, see alignment E=3e-85

Best Hits

Swiss-Prot: 64% identical to CYOC_PSEPU: Cytochrome bo(3) ubiquinol oxidase subunit 3 (cyoC) from Pseudomonas putida

KEGG orthology group: K02299, cytochrome o ubiquinol oxidase subunit III [EC: 1.10.3.-] (inferred from 92% identity to bgf:BC1003_3980)

MetaCyc: 63% identical to cytochrome bo terminal oxidase subunit III (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (202 amino acids)

>ABIE53_005342 cytochrome o ubiquinol oxidase subunit 3 (Paraburkholderia graminis OAS925)
MSNNTLSVSLDGGHGNHGSSDTVFGFWLYLMTDCVLFASLFAVFAVMSNQFAGGPSGKDL
FDIGGVAVETAALLLSSITYGFAMLAARRGKSTAVLAWLAVTFVLGLAFLALEMREFSHL
IAEGAGPARSAFLSAFFTLVGTHGLHVTVGLVWMAVLAVQILRGPGLSERQFTRLACLSL
FWHFLDIVWICVFSFVYLGSVL