Protein Info for ABIE53_005341 in Paraburkholderia graminis OAS925

Annotation: cytochrome o ubiquinol oxidase subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 668 transmembrane" amino acids 16 to 37 (22 residues), see Phobius details amino acids 58 to 81 (24 residues), see Phobius details amino acids 101 to 126 (26 residues), see Phobius details amino acids 143 to 168 (26 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 226 to 253 (28 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details amino acids 454 to 474 (21 residues), see Phobius details amino acids 493 to 518 (26 residues), see Phobius details amino acids 590 to 608 (19 residues), see Phobius details amino acids 611 to 631 (21 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 648 (647 residues), 1129.8 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 502 (447 residues), 495.2 bits, see alignment E=8.6e-153

Best Hits

Swiss-Prot: 66% identical to CYOB_PSEAE: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 96% identity to bgf:BC1003_3981)

MetaCyc: 65% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (668 amino acids)

>ABIE53_005341 cytochrome o ubiquinol oxidase subunit 1 (Paraburkholderia graminis OAS925)
MLGNLTLSAIPFDQPIIMGAGALMLVMVLAVVATLTRLHKWKWLWHEWLTSVDHKKIGVM
YIVVAVLMLVRGFVDAVMMRLQLALAYHSPGYLPPHHYDQIFTAHGVIMIFFMAMALMVG
LFNLVVPLQIGARDVAFPFLNSLSFWMTAISAILMNLSLVVGEFAQVGWLAYPPLSELQF
SPGVGVDYYIWSLQLSGVGTLITAINFFVTIVRMRAPGMTLMKMPVFTWTALCSNVLIMA
TFPILTVALALLGLDRYMGMHFFTNEAGGNAMLYLNLIWAWGHPEVYILVLPAFGIYSEV
IATFSKKPLFGYRTMVYATCAIMVLAFLVWLHHFFTMGSGADVNAFFGIMTMVIAIPTGV
KIFNWLFTIYRGRLEFSAPVLWTIGFMITFTIGGMTGVMMAIPGVDFVLHNSLVLIAHFH
NAIIGGVVFGYLAGFHYWFPKAFGFKLNEKLGKCAFWFWFVGFYASFMPLYVLGFMGMTR
RLNHYDNPAWHPWLIAAACGVVLIAIGVVFQVAQVWVSVANRNKPEYRDMTGDPWDGRTL
EWATSSPPPVYNFAIIPTVHELDAYTHMKETASGHAKTPVYRDIHMPSNTSAGLLIGMFS
LVLGFAGVWHITWLAVAALLAIVATLIVRSFGDNDGYYIPAEKVREIESKRGPAAAPVNN
RELEAVEA