Protein Info for ABIE53_005316 in Paraburkholderia graminis OAS925
Annotation: altronate hydrolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 92% identity to bge:BC1002_6153)MetaCyc: 74% identical to D-arabinonate dehydratase (Herbaspirillum huttiense)
Arabinonate dehydratase. [EC: 4.2.1.5]
Predicted SEED Role
"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)
MetaCyc Pathways
- D-galacturonate degradation I (4/5 steps found)
- D-arabinose degradation IV (4/6 steps found)
- superpathway of hexuronide and hexuronate degradation (6/10 steps found)
- D-arabinose degradation III (3/6 steps found)
- superpathway of microbial D-galacturonate and D-glucuronate degradation (19/31 steps found)
- superpathway of pentose and pentitol degradation (21/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.2.1.7
Use Curated BLAST to search for 4.2.1.5 or 4.2.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (421 amino acids)
>ABIE53_005316 altronate hydrolase (Paraburkholderia graminis OAS925) MCSASMHNPTAYVKEPAHFMGIRRGDGRIATRNYIGILTSVNCSATVARAIADHFRRDVH PDALADYPNVDGVIALTHGLGCGIDTQGEGIRILRRTLAGYAVHPNFASVLFVGLGCETN QIDGVLEAGGLGSSDLKLRSFTIQDSGGTRKTIERGIAMVQEMLADANRIQRVPVPASHL SIGLQCGGSDGYSGISANPALGAAVDRVVRHGGTAILSETPEIYGAEHLLTRRAVSPAVG EKLLARIAWWQDYCARNGGALDNNPSAGNKAGGLTTILEKSLGAVAKGGTTNLVDVYEYA QPVAAKGLVFMDSPGYDPVSATGQVASGANVICFTTGRGSAYGCAPSPSLKFATNNTLWE RQADDIDLNCGGVIDGSASIDELGEAIFQMMLDCASGTRTKSELHGYGQSEFVPWQVGVV T