Protein Info for ABIE53_005215 in Paraburkholderia graminis OAS925

Annotation: arsenical pump membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 58 to 75 (18 residues), see Phobius details amino acids 99 to 126 (28 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 176 to 194 (19 residues), see Phobius details amino acids 219 to 237 (19 residues), see Phobius details amino acids 243 to 261 (19 residues), see Phobius details amino acids 273 to 291 (19 residues), see Phobius details amino acids 356 to 381 (26 residues), see Phobius details amino acids 393 to 415 (23 residues), see Phobius details PF03600: CitMHS" amino acids 22 to 346 (325 residues), 147.9 bits, see alignment E=6.3e-47 PF02040: ArsB" amino acids 28 to 409 (382 residues), 110.8 bits, see alignment E=1.6e-35 PF07158: MatC_N" amino acids 56 to 139 (84 residues), 27.2 bits, see alignment E=5.4e-10

Best Hits

KEGG orthology group: K03893, arsenical pump membrane protein (inferred from 96% identity to bug:BC1001_5310)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (416 amino acids)

>ABIE53_005215 arsenical pump membrane protein (Paraburkholderia graminis OAS925)
MTSIFLSWGIAAFATAGVITRPFKWPEAVWAVAGAVLLVSLGLLPLHLAMEAVGKGTDVY
LFLFGMMLLSEVGRREGLFDWVAVLAVNHAQGSPRKLFMLVYLVGVVITAFLSNDATAVV
LTPAVFAAAKKAKTDPLPLLFVCAFVANAASFVLPISNPANIVLYGNHTPALGPWLMRFA
LPSLLSIGATYALLRWTQRDALAGICEANLEPLRLSSSGRVALAGIAVTAVVLLAVSAFD
IPLGLPTAILGALTAIVVLIQERKSPLPMIREISWSVLPLVAALFVLVEMLDHTGVIRML
AALTQEGAAHNEASTAGWAGMAIAIGSNLMNNLPAGLIASSTVMQAHSPERVIDALLIGV
DLGPNMSITGSLATILWLNAIRREGEDVSFMKFLKVGVVVMLPALVLALGARILIG