Protein Info for ABIE53_005011 in Paraburkholderia graminis OAS925

Annotation: DNA-binding LacI/PurR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 PF00356: LacI" amino acids 3 to 48 (46 residues), 58.7 bits, see alignment 8e-20 PF00532: Peripla_BP_1" amino acids 61 to 303 (243 residues), 103.6 bits, see alignment E=2.7e-33 PF13407: Peripla_BP_4" amino acids 63 to 310 (248 residues), 56.2 bits, see alignment E=8e-19 PF13377: Peripla_BP_3" amino acids 170 to 332 (163 residues), 119.8 bits, see alignment E=2.7e-38

Best Hits

KEGG orthology group: None (inferred from 55% identity to bpy:Bphyt_4583)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (338 amino acids)

>ABIE53_005011 DNA-binding LacI/PurR family transcriptional regulator (Paraburkholderia graminis OAS925)
MVTLSEVAKRAHVTAATVSNVLRNREKVRPETAERVLKAIADLGYRPNLNARALAEGRSS
TLALMLSNISNPFYPEFVLAAERAARKAGHFLMVCNTDDDAEIGRAYLNQIAGTLADGVL
VMNTDIAINDLCASATHSAPILLAMWEHPETPPALPCIAVDFARAGELAAQHLLELGHRE
VGLLVGDGCGGLQDARSNGFRATMRAAGVEADTAAVLQVRDSIDAGYTACMQLMAVRPFV
TAIFATNDLLAIGAAQALITLGRAVPDDVSVIGITDIQLAHQVHPALTTVAIQTAQIAEL
SINSLIRLIQTPERQPSMVLGPPPQLVVRASTGPRRRR