Protein Info for ABIE53_004928 in Paraburkholderia graminis OAS925

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 PF13377: Peripla_BP_3" amino acids 118 to 287 (170 residues), 107.3 bits, see alignment E=1.4e-34 PF12833: HTH_18" amino acids 318 to 397 (80 residues), 69.7 bits, see alignment E=3.2e-23 PF00165: HTH_AraC" amino acids 365 to 395 (31 residues), 29.2 bits, see alignment (E = 1.2e-10)

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 96% identity to bug:BC1001_5064)

Predicted SEED Role

"Xylose activator XylR (AraC family)" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (407 amino acids)

>ABIE53_004928 LacI family transcriptional regulator (Paraburkholderia graminis OAS925)
MTRPQTPQTTHRIALLFNANKVYDREIITGIGNYLLSTRVAWDLFLEDDFRCRLTGIERF
DGDGIIADFDDPAVSEALRDCPLPVVAVGSSFEDPAQYPPDLPYIATDNSKLVSLAYTHL
IGAGLEHFALYSLPQAQENRWAQQRELAFAHLRNADGHSAEQIQSEIYRGLSTSAPSWNQ
ATEQLTAWLRELPKPVGIIAVTDARARHLLQACLIAGIPVPEEVAIIGIDNDPLTRTLTR
IPLSSVIQGTEEMGRTAAHLLHQMLHGARFPGRRILVPPVGINVLESTRHQPLASPYVMR
ARHFIRQYACQGIRTEQVADYVGVSRSSLEEYFRRERKCTVHQEILRHKLDVAKALLAKR
DASSAEVAIRCGFTSLQYMYAVFRRELGCTPREYQERASLTQASTPG