Protein Info for ABIE53_004900 in Paraburkholderia graminis OAS925

Annotation: FAD/FMN-containing dehydrogenase/Fe-S oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1006 PF01565: FAD_binding_4" amino acids 58 to 194 (137 residues), 119.9 bits, see alignment E=1.7e-38 PF02913: FAD-oxidase_C" amino acids 283 to 535 (253 residues), 163.4 bits, see alignment E=2e-51 PF13183: Fer4_8" amino acids 574 to 650 (77 residues), 33.6 bits, see alignment 1.2e-11 PF13534: Fer4_17" amino acids 576 to 651 (76 residues), 25.9 bits, see alignment 2.9e-09 PF02754: CCG" amino acids 758 to 831 (74 residues), 19.4 bits, see alignment 2.4e-07

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 89% identity to bug:BC1001_5033)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.14

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1006 amino acids)

>ABIE53_004900 FAD/FMN-containing dehydrogenase/Fe-S oxidoreductase (Paraburkholderia graminis OAS925)
MSDAPRYAQKPAAPFVASPRLLEHVQADLRATLRGEVRFDAGSKALYASDASNYRQIPLG
AVVPADVDDLVAALEVCRRNDVPFLTRGGGTSQNGQCVNVAVVADTSKYVNRVVSVDPQN
RTALVEPGVICDTLRDAAEEHGLTFAPDPATHSRCTLGGMIANNSCGAHSVMGGKTVENI
EALEIATYDGARFWVGPTSDAELDDIIATGGRQGEIYAKLRDLRDRYAERIRGEFPQIRR
RVSGFNLDQLLPENGFNVARALVGTEGTCAVTLQAKVRLVHSPACRVLLVLGFSDIYTAA
DAVPHFNRFSPIAIEGLDRAIIRGLQARGLKSDEIALLPDGDAWVVLEFGSDTVADALTQ
ANDAAAYFKSGAAGADISGLVVEDKHKQQKIWSIRETGASAVALSIDPSKPDPIVGWEDA
AVDPLRLGDYLRKFQALVDRFGYETCLYGHFGDGCVHARITFDIRTAEGVGKWRSFLREA
AQLVVDFGGSLSGEHGDGQAKAEFLPIMYGPEILQAMQEFKAIWDPLNRMNPGKVVHAYR
ADENLRMGPAYKPVTLTTKLTFASREGDGMQRAVERCIGMGKCRSLDGGTMCPSFRATRE
EKFSTRGRAHLFWEMLQGEVIEDGWNSTEVKDALDTCLACKGCKSDCPTHTDMASYKAEF
LSHYYERHRRPRQAMFMGRIGQWAPLASRFARVTNLMTSAKPLAHIGKWIAGVARERHLP
VFAPRTFRAMEARRVKVGSAAANEPSRKVILWVDTFNDHFSPEIATAALEVLTRIGYHVV
LPRKRLCCGRPLYDYGLLDEARALLRSAVNELADDIEAGVPVVGLEPGCLSIFKDELLKQ
LPDDPVAKRLSDQTFLFADFVARADYEWPKLDADVVVHGHCHQKSIFGMKGDTELLDKLG
VRWTLLDTGCCGMAGSFGFSADHYELSMKIAEDKLLPLVRNAPAEAIVVTNGFSCREQIE
QGAGRHTLHIAQLVVKAFEPMAETAPFPIRNDGSQPAHAAQPTPHA