Protein Info for ABIE53_004729 in Paraburkholderia graminis OAS925
Annotation: D-threo-aldose 1-dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 51% identical to PLD_MICLT: Pyridoxal 4-dehydrogenase (pld1) from Microbacterium luteolum
KEGG orthology group: None (inferred from 94% identity to bug:BC1001_4837)Predicted SEED Role
"L-fuco-beta-pyranose dehydrogenase (EC 1.1.1.122)" (EC 1.1.1.122)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.1.1.122
Use Curated BLAST to search for 1.1.1.122
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (346 amino acids)
>ABIE53_004729 D-threo-aldose 1-dehydrogenase (Paraburkholderia graminis OAS925) MTATIGSKVRQRRRVGRSALELTGLSLGSAPLGGLYRDLSDEEAHATIAAAWDAGVRYFD TAPHYGHTKAEHRLGDALRRYPRGEYALSTKVGRRFVPRTTPYDGKEGWQNPLPFEAIYD YTHDGILRSFEDSQQRLGIVDIDILLVHDIGRVTHGDNNPHYWRQLTEGGGFRALDELRS AGAVKAVGLGVNESAVILDAMAEFDIDCALLAGRYTLLEQTTLDDLLPACEQRGVSILLG GAFNSGILARGVEGDLKFNYGEAPREVIERVARLEAVCRAHGVPLAAAALQFPYAHPAVA TVLTGARSAEELRENAASFELPIPAALWSALRDEGLLDARAPAPED