Protein Info for ABIE53_004469 in Paraburkholderia graminis OAS925

Annotation: subfamily B ATP-binding cassette protein HlyB/CyaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1018 transmembrane" amino acids 127 to 148 (22 residues), see Phobius details amino acids 460 to 482 (23 residues), see Phobius details amino acids 496 to 521 (26 residues), see Phobius details amino acids 570 to 594 (25 residues), see Phobius details amino acids 600 to 618 (19 residues), see Phobius details amino acids 678 to 702 (25 residues), see Phobius details amino acids 715 to 740 (26 residues), see Phobius details PF00027: cNMP_binding" amino acids 38 to 122 (85 residues), 61.8 bits, see alignment E=1e-20 amino acids 169 to 256 (88 residues), 64.2 bits, see alignment E=1.7e-21 PF03412: Peptidase_C39" amino acids 306 to 431 (126 residues), 130.1 bits, see alignment E=1e-41 PF00664: ABC_membrane" amino acids 463 to 730 (268 residues), 158.9 bits, see alignment E=4.3e-50 PF00005: ABC_tran" amino acids 796 to 945 (150 residues), 115.3 bits, see alignment E=7.2e-37

Best Hits

KEGG orthology group: None (inferred from 98% identity to bug:BC1001_4588)

Predicted SEED Role

"ABC-type bacteriocin/lantibiotic exporter, contains an N-terminal double-glycine peptidase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1018 amino acids)

>ABIE53_004469 subfamily B ATP-binding cassette protein HlyB/CyaB (Paraburkholderia graminis OAS925)
MDAPQTAPSAAEFLASVEILSPFSRDEIERLAEYAQARFYSFGETVCSTGETADGLYIVR
SGSVRIFVEEHGKETSMGVRKSGEIFADIAMLRTYVHEASVRASAKTELLFIPRAAIEPV
MAGNQAALAFVASYVAINSAGGFVAQLFDLRGKLNKAELEEYVRSVGVKRVAAGKEILRQ
DARDDRRLYVVRQGEVRIVRHEEGRDYTLATLGEGEIFGEKACLMRQEQMASVIASTDAR
LLVIPERTVHFILERNPKLREVLDERIRYGDRELQRQKRLEQRRKLPLMLDLQSKPALGE
KIIKRFALVEQAEEMDCGAACLAMICRHYSIPMTLGKLRELANVTTQGATLDSLARAGES
LGFTARGVQCTFDSLRGFDLPFIVHWEGYHYVVVYGLSTEYVWIADPALGFRKLTVEDFE
RGWSGTCLLFTGGPQLVQMSAARSPWIRFVGYLKPYRKILGHLFLATFVIQVLGVIPPLI
IQNILDGVIVHQNVSLLHLLIGGLIIANVFSQLMSSIRAYLANFMVRNMDFAMMSQFFKH
TLSLPFSFFAKRKTGDIFARFQENQTIRAFLTESTVTTALNLLMVFIYFTIMFVYNVKMT
LVLIGFVIPIMALTALATPKIKNYAREVFTASTESKSFLMEALAGVETVKGMGIERPVRL
RWEKKYAKALEVQYRAHAFNILVGLGSQLLNAATTIAILWVGANLVLAREMTIGQLIAFN
AFMGSVLGPLMGLVGLWSMLNDAGVAMERLGDVLDIEPEQKPEDLPSRVMLPELQGEISL
SGVYFRYGENDSAYVLENISFDIKPGELVAIVGRSGSGKTTLAKLLVGFYAPSEGKMSID
GYDLSVVDKAYFRAQIGYVMQSNLLFSGTIAENIASGDDAPDRRRIEEVARMADAHAFIS
KMPLGYEQIVGERGIGLSGGQIQRLCIARALYHDPRLLVFDEATSALDSQSESNILGNMH
DILKGRTAVIIAHRLSTIMRADKILVLYEGAIVEQGRHEELLQRGGMYYQLVQKQLSA