Protein Info for ABIE53_004393 in Paraburkholderia graminis OAS925

Annotation: signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 transmembrane" amino acids 28 to 50 (23 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details PF02518: HATPase_c" amino acids 241 to 345 (105 residues), 73.7 bits, see alignment E=1.7e-24

Best Hits

KEGG orthology group: None (inferred from 64% identity to bgf:BC1003_4216)

Predicted SEED Role

"periplasmic sensor signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>ABIE53_004393 signal transduction histidine kinase (Paraburkholderia graminis OAS925)
MTFIHWTVSREVSPNSLLKIRTRAARRWLLWTARVLAVFIAISMPAAHAATLYAQPYRAG
GYLLPLLWLLATGFAVLAAALAVHAYEQRSCIARLAAAIEQRSSTGTLPQSLPEFGPPTV
ARLARAINGAQRCEAERVAELLDVLAAYAHDLRTPLTRMALRCERVDEGELRNAMERDIA
EMNELVEASLACARMQCCAGAPLRRFDADGLLGALVDNYKDMGRSVELEGEVGHPVVTCP
HALRRVLVNLIDNGLRYGNDVRLCVRVDARRVVVAVVDSGPGIVPAEMEAVFAPWYRAPQ
TAARAPGSGLGLAIARRLTLAMQGELQLENRHSGGLEARLTLPLAA