Protein Info for ABIE53_004213 in Paraburkholderia graminis OAS925

Annotation: PTS system fructose-specific IIC component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 285 to 309 (25 residues), see Phobius details amino acids 319 to 343 (25 residues), see Phobius details amino acids 358 to 384 (27 residues), see Phobius details amino acids 400 to 421 (22 residues), see Phobius details amino acids 440 to 458 (19 residues), see Phobius details amino acids 479 to 503 (25 residues), see Phobius details amino acids 515 to 534 (20 residues), see Phobius details amino acids 541 to 561 (21 residues), see Phobius details amino acids 582 to 603 (22 residues), see Phobius details PF02302: PTS_IIB" amino acids 7 to 97 (91 residues), 39.3 bits, see alignment E=4.3e-14 amino acids 135 to 223 (89 residues), 64 bits, see alignment E=8.3e-22 TIGR00829: PTS system, Fru family, IIB component" amino acids 134 to 216 (83 residues), 113.8 bits, see alignment E=3.5e-37 TIGR01427: PTS system, Fru family, IIC component" amino acids 264 to 604 (341 residues), 473.9 bits, see alignment E=3.5e-146

Best Hits

KEGG orthology group: K02769, PTS system, fructose-specific IIB component [EC: 2.7.1.69] K02770, PTS system, fructose-specific IIC component (inferred from 91% identity to bug:BC1001_4251)

Predicted SEED Role

"PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component" in subsystem Fructose utilization (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (611 amino acids)

>ABIE53_004213 PTS system fructose-specific IIC component (Paraburkholderia graminis OAS925)
MDKLIGLVSSPQQSASPMVAAQALNRAAQRRGASLAVETRSALGVQHPLNAAQIDAAQAV
LIAADADERIDETPFAGKTIHRVSLDDAIREADAVLARVAANAGANVASNTAQGAGNAHA
AQGPQASPRALKIVAITSCPTGIAHTFMAAEGLAQGAKSLGHEIHVETQGSVGAQNTLSD
EQIAVADLVVIAADTQVDKSRFRGKPIYETGTKGAIGKGAALIERAIAEASVDGNAPASQ
ASASASANGQSAAGGALADQVAAAKKQRSAKASGPYRHLMTGVSFMLPFVVAGGLLIAIS
FALGGIYAFDDAHKGTLAWALFQIGAKSAFALMVPVLSGYIAYSIADRPGITPGMVGGML
AASLGAGFLGGIISGFLAGYTALLISRKLKLHRNLEGLKPVLIIPLVSTLVVGLLMIYVV
GTPVATALHGLENWLRSMQTGSAVTLGLLLGAMMAFDMGGPVNKAAYAFSTGLIASQVYT
PMAAAMAAGMTPPLGIALATWIFRNRFVADEREAGNAAAVLGMAFITEGAIPFAARDPMR
IIPACVIGSAITGAISMASAVDLKVPHGGIFVLPIPNAVTHLGMYVLAIAVGTVVTALAV
GVLKRPVQVAA