Protein Info for ABIE53_004128 in Paraburkholderia graminis OAS925

Annotation: HAD superfamily hydrolase (TIGR01509 family)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00702: Hydrolase" amino acids 7 to 180 (174 residues), 110.5 bits, see alignment E=2.8e-35 PF12710: HAD" amino acids 8 to 179 (172 residues), 45.8 bits, see alignment E=2e-15 PF13419: HAD_2" amino acids 8 to 180 (173 residues), 98.6 bits, see alignment E=9.9e-32 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 70 to 181 (112 residues), 32.9 bits, see alignment E=8.2e-12 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 75 to 183 (109 residues), 35.8 bits, see alignment E=8.5e-13 PF13242: Hydrolase_like" amino acids 144 to 218 (75 residues), 38.4 bits, see alignment E=1.9e-13

Best Hits

KEGG orthology group: None (inferred from 99% identity to bug:BC1001_4163)

Predicted SEED Role

"2-deoxyglucose-6-phosphate phosphatase 1 (EC 3.1.3.68)" (EC 3.1.3.68)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.68

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>ABIE53_004128 HAD superfamily hydrolase (TIGR01509 family) (Paraburkholderia graminis OAS925)
MRIQTSFLFDLDGTLVDSVYQHVLAWKEALDSEGISLSVWRIHRKIGMSGGLFTNQLLRE
THGDISAERGERLRHAHAAAYKRLRAQVCPLPGARELLDALTQAGTPWAVATSGRMETAA
VNLEALGVDPSKAVVVTRDDVKYAKPDPDLFIAAAERLGVQIEHSVVVGDSIWDMLAARR
CRALGVGLLSGGYGTEELERAGALRVYDDPAALLDHLDEVASRP