Protein Info for ABIE53_003951 in Paraburkholderia graminis OAS925

Annotation: dipeptide transport system substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details PF00496: SBP_bac_5" amino acids 90 to 470 (381 residues), 336.4 bits, see alignment E=1.1e-104

Best Hits

Swiss-Prot: 48% identical to HBPA_HAEIN: Heme-binding protein A (hbpA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 81% identity to bgd:bgla_2g06830)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) or Bacterial Chemotaxis (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (552 amino acids)

>ABIE53_003951 dipeptide transport system substrate-binding protein (Paraburkholderia graminis OAS925)
MTFRSVFPGASLRHALFRGSRLGVSMVLSGALLMNGASVHAAPAGTLVFCSEGSPAGFDP
GQHTTSTDFDASTNTVYNGLVQFRRGTLDLEPALATSWDISADQRTYTFHLRGGVKFHTT
AWFRPTRDFNADDVLFTFNRMLHADDPFRKAYPSSFPYFSDLGFDRNIESIEKVDALTVR
FRLKEPDVIFVRNLAMSFASILSAEYADKLSAAHREADINQLPVGTGPFVFRSYQKDALI
RYDANPVYWRPDDVKLAHLIFAITPDPAVRMQKLASGECQVSVFPRPADLEVVKRNAALT
AVSGVGFNVGFVAYNTQHAPLNRVEVRRALDMAIDKPAIIQSVFSGNATIASNPMPPAQW
SYNKQLKDAPYDPAKAKALLAQAGFPNGFEISLWAMPVQRPYNPNAQLMAQLIQQDWAKI
GVRAKIVSYEWGEYNRRAKQGGEHDAMLYGWSGDNGDPDNWLGTLLGCDAVHGSNVSKWC
DPAFNALIDKARAAANVDERTALYQQAQVIFKQQVPYTPIAHSIVSLPVSKRVKGMVFSP
LGSHRFEGVWLE