Protein Info for ABIE53_003922 in Paraburkholderia graminis OAS925

Annotation: non-specific serine/threonine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 957 transmembrane" amino acids 428 to 448 (21 residues), see Phobius details PF07714: PK_Tyr_Ser-Thr" amino acids 156 to 373 (218 residues), 80.8 bits, see alignment E=2.1e-26 PF00069: Pkinase" amino acids 156 to 374 (219 residues), 118.4 bits, see alignment E=7.8e-38 PF03109: ABC1" amino acids 218 to 307 (90 residues), 23.9 bits, see alignment E=4.3e-09 PF01636: APH" amino acids 260 to 312 (53 residues), 28.3 bits, see alignment 3.2e-10

Best Hits

KEGG orthology group: None (inferred from 90% identity to bgf:BC1003_4184)

Predicted SEED Role

"Serine/threonine protein kinase (EC 2.7.11.1)" (EC 2.7.11.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (957 amino acids)

>ABIE53_003922 non-specific serine/threonine protein kinase (Paraburkholderia graminis OAS925)
MNDIYSRLGAGGARARQLFLLIEARARRLFARRAAPVSSSSVYRREQVALDARPADADDG
LTVVQPAVGVSSRASWDDATVVKPASRSVSHAGSEEVRSNDANNSDVNDSDVNGSSASDS
KSSDSSLNRDTWQRVAQARSGDHASVGKLLKGRFLLERELGRGGMGVVYLARDERKVEAR
DRDPYVAVKVLNDEFRRHPDSLIALQREARRAQRLAHDNIVHVYDFDKDGTIVFMTMEYI
DGTDLRTLIRERPSGMPFREAWPLIDAMARALQRAHASGIVHSDFKPGNVMVTRDGVPKV
FDFGIARAGLAAAGAAGEQTVFDAGTLGAMTPAYASLDMIEGAAPSVRDDVYALGCVVFE
LLTGRHPFDRHSADVALRESAVPPPVPGLGRRQYRALCQAVAFRGGERLQTVGALVEALR
PRKMRERLLPYCAGALAVAVLAAGASAWHSQHRHRQLEATIARFADSDSRHYANEDQAVA
ALALLGVDERERLVLNQNDLIQRFLASRLDAYWSPPLGRIDYAAAQHVFQIRDQLKLFSP
EFDVRRKQIDDERADMLAKLASSLDEALDRDALFDDQPGSAADILQRIRMLDPGSALLKS
PQIESRYDAAIGQSLDSARFDEARARIALALQLFPDSSRLQRRRGQLAAAAASATQNHGT
PAAAMSVPDARRSLVELAANPSASASWLDGVSRAMSALQNDASSETGTAIDALADGIVAA
ASRVTDPLLAHRTLDVIEVGLRYAPHSPGLSAQRDRMLQLLQQQRIDQLTASGDAAAQMD
ALRLAAAANDGARALAALNRMRALEPGNAFLTSGAPQLVANAYLGNARALGRAGHLQDAA
RVASQGADALSGDQKLGDAAQRYLLAAAILAARDQPMADPDLQALQARFDTAQAADPEAM
KQMERDIGASIALPPGGLSALLEQIKARVESGDAASAAASVSMTLPARSDRHSQANA