Protein Info for ABIE53_003603 in Paraburkholderia graminis OAS925
Annotation: preprotein translocase subunit SecA
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 90% identical to SECA_BURA4: Protein translocase subunit SecA (secA) from Burkholderia ambifaria (strain MC40-6)
KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 90% identity to bac:BamMC406_0497)Predicted SEED Role
"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (936 amino acids)
>ABIE53_003603 preprotein translocase subunit SecA (Paraburkholderia graminis OAS925) MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRAKTDEFRQRIASGESL DKLLPEAFAVCREASKRVLKMRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNA LSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQMDHDAKQQAYAADITYGTNN EFGFDYLRDNMVYEPEARVQRGLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLAEWGLIGEGES LYAPQNITLMHHVYAALRAHTLFYKDQHYVVQNGEVIIVDEFTGRLMAGRRWSDGLHQAV EAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTEAYEFNEIYGLETVVVPTNRP PKRIDKQDQIYKTAKERYDAVIRDIRDCYERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHAREAEIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQASFIELDETIPEDEK RRRIQKLHDEWQALHDQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL EDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVSRSIESAQRKVEARNFDIRKQLLEYDD VSNDQRKVIYQQRNELLEANDITETIGAMRHGVIADIVHQFVPAGSIEEQWDVPELEEVL RNEWQLDLAIQEMINESNSITSDEILEAVEAAADEAYEAKVELVGRESFSAFERSIMLQT LDRSWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKLEVTRIVMNVQ IQSPEQLEQAAEQMEEQGGHLENVEFRHAEFAEASAAAPAAVEAATAAMIGDAMSHASSS QAASAVGADGVPKVGRNDPCPCGSGKKYKQCHGKIA