Protein Info for ABIE53_003558 in Paraburkholderia graminis OAS925

Annotation: DNA-binding IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF09339: HTH_IclR" amino acids 79 to 127 (49 residues), 31 bits, see alignment 1.7e-11 PF01614: IclR" amino acids 192 to 319 (128 residues), 71.1 bits, see alignment E=8.4e-24

Best Hits

KEGG orthology group: None (inferred from 92% identity to bug:BC1001_3055)

Predicted SEED Role

"D-galactonate regulator, IclR family" in subsystem D-galactonate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>ABIE53_003558 DNA-binding IclR family transcriptional regulator (Paraburkholderia graminis OAS925)
MNKAMPNHAESAAEAELTPRADHASSPAPRASATAAKAPRPPATAAKAPRAAAQPTIVNE
IALPSTLLDITPQQAGTQTLLRGLAILEAAAAGVRDLRTFGAALGTTRSTTHRLVSSLVQ
ARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLESLAEQTLDTIHLGVRDGDDVL
YIDKIPGTRGLEMRSRVGHRMPLASTGIGKAMMLDLKPELWQSLFDASRRALASVTFKPD
NRPDAQTFMQRMTNYAAGGYTFDLEENEASIRCVAAPVRDASGAIVAALSVASTIPYMSL
ERMDELIPVVQREARAISEELGWRAPQPTTRRIKR