Protein Info for ABIE53_003265 in Paraburkholderia graminis OAS925

Annotation: aromatic amino acid transport protein AroP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 46 to 63 (18 residues), see Phobius details amino acids 98 to 121 (24 residues), see Phobius details amino acids 126 to 144 (19 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 274 to 299 (26 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details amino acids 399 to 421 (23 residues), see Phobius details amino acids 427 to 443 (17 residues), see Phobius details PF00324: AA_permease" amino acids 18 to 452 (435 residues), 415.1 bits, see alignment E=3.6e-128 PF13520: AA_permease_2" amino acids 22 to 440 (419 residues), 122.3 bits, see alignment E=2.7e-39

Best Hits

Swiss-Prot: 71% identical to AROP_SHIFL: Aromatic amino acid transport protein AroP (aroP) from Shigella flexneri

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 95% identity to bxe:Bxe_A0842)

MetaCyc: 71% identical to aromatic amino acid:H+ symporter AroP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-56; TRANS-RXN-76; TRANS-RXN-77

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (464 amino acids)

>ABIE53_003265 aromatic amino acid transport protein AroP (Paraburkholderia graminis OAS925)
MNNALQQEGLKRGLKNRHIQLIALGGAIGTGLFLGSASVLQAAGPSMILGYAIGGIIAFM
IMRQLGEMVAQEPVAGSFSHFAYKYWGDFPGFLSGWNYWVLYVLVSMAELTAVGTYVHYW
WPGVPTWVSALVCFAGINAINLANVKAYGETEFWFAIVKVVAVIGMILFGGYLLISGHGG
PQASVTNLWSHGGFFPHGFHGLFTMLAVIMFSFGGLELIGITAAEADEPQKSVPKAVNQV
IYRILIFYICSLAVLLSLYPWNEVAAGGSPFVMIFSQIGSTLTANVLNVVVLTAALSVYN
SGVYANSRMLYGLAEQGNAPRALMKVDRRGVPYMAIGLSALATFTCVIVNYLIPAEALGL
LMALVVAALVLNWALISLTHLKSRRAMVAAGETLVFKSFWFPVSNWICLAFMALILVILA
MTPGLSVSVWLVPVWLVVMWAGYEFKRRRAAAHGSAARVVGRQS